Treatment and Screening
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2015 STD Treatment Guidelines
Recommendations for treating persons who have or are at risk for STDs. Includes regimens, evidence tables, wall chart, and pocket guide. The 2015 Guidelines are the most current version of this document.
CDC 2021 Sexually Transmitted Infection (STI) Treatment Guidelines Update Webinar | Transcriptword icon – This webinar provided an overview of the proposed updates to CDC’s 2015 STD Treatment Guidelines. During the webinar, representatives from CDC’s Division of STD Prevention addressed questions and comments from partners, stakeholders and other interested parties. Comments and feedback made during the webinar will be considered prior to finalizing the updated STI Treatment Guidelines for publication. A recording of the webinar is expected to be available soon.
CDC’s updated recommendations for the treatment of uncomplicated gonorrhea in adolescents and adults: two-drug approach no longer recommended; treat with just one 500 mg injection of ceftriaxone.
There is currently a national shortage of: Azithromycin; Gemifloxacin; Erythromycin (0.5%) Ophthalmic Ointment; STI Diagnostic Test Kits and Laboratory Supplies
Recommendations for Providing Quality STD Clinical Services (STD QCS)
CDC Recommendations for Providing Quality STD Clinical Services, 2020 (STD QCS) MMWR and a graphic explaining how STD QCS and the STI Treatment Guidelines can work together to optimize care.
Expedited Partner Therapy
Providing prescriptions or medications to the patient to take to his/her partner without the health care provider first examining the partner.
Additional Resources
General STD treatment updates and resources, including Dear Colleague Letters, podcasts, and scientific articles.
2020 Update to CDC’s Treatment Guidelines for Gonococcal Infection (December 17, 2020) – Special Policy Note: Includes CDC’s updated recommendation for treating gonococcal infections, as well as alternative treatment regimens.
STD Care and Prevention Guidance During Disruption of Clinical Services (September 8, 2020)
Morbidity and Mortality Weekly Report (MMWR): Missed Opportunities for Prevention of Congenital Syphilis – United States, 2018 (June 4, 2020)
- Dear Colleague Letterpdf icon: from Dr. Gail Bolan, Director, Division of STD Prevention
The Diagnosis, Management and Prevention of Syphilis: An Update and Reviewpdf iconexternal icon – A clinical guidance document for use in the diagnosis and management of syphilis. Based on content from the 2015 CDC STD Treatment Guidelines, and developed by the NYC Department of Health and Mental Hygiene Bureau of Sexually Transmitted Infections and the NYC STD Prevention Training Center. (March 2019)
Syphilis Pocket Guide for Providerspdf icon – Updated booklet for providers containing need-to-know details on the diagnosis, treatment, and prevention of syphilis. (November 30, 2017)
National STD Curriculumexternal icon – An online modular learning experience that helps users learn how to manage STDs. It is continuously updated and integrates the most recent STD Treatment Guidelines. Free CME/CNE available. (November 1, 2017)
