These guidelines for the treatment of persons who have or are at risk for sexually transmitted diseases (STDs) were updated by CDC after consultation with a group of professionals knowledgeable in the field of STDs who met in Atlanta on April 30–May 2, 2013. The information in this report updates the Sexually Transmitted Diseases Treatment Guidelines, 2010 (MMWR Recomm Rep 2010;59 [No. RR–12]). These updated guidelines discuss 1) alternative treatment regimens for Neisseria gonorrhoeae; 2) the use of nucleic acid amplification tests for the diagnosis of trichomoniasis; 3) alternative treatment options for genital warts; 4) the role of Mycoplasma genitalium in urethritis/cervicitis and treatment-related implications; 5) updated HPV vaccine recommendations and counseling messages; 6) the management of persons who are transgender; 7) annual testing for hepatitis C in persons with HIV infection; 8) updated recommendations for diagnostic evaluation of urethritis; and 9) retesting to detect repeat infection. Physicians and other health-care providers can use these guidelines to assist in the prevention and treatment of STDs.
Downloads and Resources
Download the 2015 STD Treatment (Tx) Guide app, an easy-to-use reference that combines information from the STD Treatment Guidelines as well as MMWR updates, and features a streamlined interface so providers can access treatment and diagnostic information. The free app is available for Apple devices and Android devices.
A limited amount of Wall Charts and Pocket Guides are available for you to order from CDC-INFO on Demand. To print your own, download the high-resolution print files below and take them to a commercial printer.
Public Domain and Reprinting
General text information, publications available for download, and graphs developed by CDC and presented on CDC’s website are works of the United States Government and are in the public domain. This means that they are meant for public use and are not subject to copyright law protections. Permission is not required for use of public domain items. But, CDC does ask that you credit the original institution and contributor, when known, whenever the item is used in any publicly distributed media.
You are also free to adapt and revise these materials, provided the information is distributed free of cost; however, you must remove the CDC name and logo if changes are made. Additionally, in accordance with 42 U.S.C. Section 1320b-10, no person may, for a fee, reproduce, reprint, or distribute any item consisting of a form, application, or other publication of the United States Department of Health and Human Services (HHS) unless such person has obtained specific, written authorization for such activity. Therefore, if you wish to sell the CDC materials presented on CDC’s website, you must first obtain permission to do so from CDC.
Procaine Penicillin G Shortage (September 19, 2016)
2015 CDC STD Treatment Guidelines Update Webinar in Spanish – April 5, 2016, View recording, CE credits available
Clinical Advisory: Ocular Syphilis in the United States (October 16, 2015)
New STD Guidelines for 2015 – CDC Expert Commentary featuring Kimberly Workowski, MD (October 5, 2015)
2015 STD Treatment Guidelines Overview Webinar – June 22, 2015, View Recording, CE credits available. (June 23, 2015)
- Questions & Answers (February 17, 2016)
- Page last reviewed: June 4, 2015
- Page last updated: January 25, 2017
- Content source: