FIGURE J. DISTRIBUTION OF AZITHROMYCIN MINIMUM INHIBITORY CONCENTRATIONS (MICs) AMONG GISP ISOLATES, 2014-2018

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CLINIC Azithromycin Percentage
2014 2015 2016 2017 2018
ALBUQUERQUE <=0.03 19.3 17.4 17.9 6.6 6.5
0.06 15.8 20.0 24.3 20.4 17.3
0.125 23.7 20.0 13.6 26.3 25.4
0.25 28.1 34.8 28.6 38.7 20.0
0.5 11.4 6.1 11.4 4.4 24.3
1.0 1.8 1.7 3.6 3.6 5.9
2.0 . . 0.7 . 0.5
ANCHORAGE <=0.03 . . . . 23.5
0.125 . . . . 11.8
0.25 . . . . 58.8
0.5 . . . . 5.9
ATLANTA <=0.03 16.7 18.4 9.8 3.5 5.6
0.06 21.3 11.4 12.2 13.4 11.9
0.125 19.0 28.8 23.3 32.8 44.1
0.25 22.0 23.1 26.1 35.8 30.1
0.5 18.3 15.1 20.6 8.0 3.5
1.0 2.3 2.7 5.9 6.0 4.9
2.0 0.3 . 1.4 . .
>=4.0 . 0.7 0.7 0.5 .
BIRMINGHAM <=0.03 3.1 1.1 2.1 15.4 7.1
0.06 11.7 5.1 3.7 9.8 7.1
0.125 27.8 28.6 19.0 34.1 37.8
0.25 37.7 49.7 43.4 34.1 32.7
0.5 18.4 14.3 24.9 4.1 7.1
1.0 0.9 1.1 6.9 1.6 7.1
2.0 0.4 . . 0.8 1.0
BOSTON <=0.03 3.7 2.6 . 3.2 11.4
0.06 3.7 7.9 . 6.5 5.7
0.125 14.8 18.4 10.3 9.7 25.7
0.25 14.8 36.8 31.0 54.8 28.6
0.5 48.1 23.7 31.0 19.4 17.1
1.0 11.1 5.3 6.9 3.2 8.6
2.0 3.7 5.3 17.2 . 2.9
>=4.0 . . 3.4 3.2 .
BUFFALO <=0.03 14.9 15.7 4.3 26.5 14.7
0.06 11.5 21.4 3.5 12.5 12.9
0.125 23.0 31.4 40.4 37.5 33.7
0.25 19.5 20.0 26.2 15.4 23.9
0.5 20.7 8.6 18.4 6.6 14.7
1.0 8.0 2.1 5.7 0.7 .
2.0 . 0.7 0.7 0.7 .
>=4.0 2.3 . 0.7 . .
CHICAGO <=0.03 12.4 8.7 6.4 7.0 5.8
0.06 11.6 20.7 10.4 18.4 13.6
0.125 15.5 26.7 24.8 33.5 31.1
0.25 16.3 29.3 26.4 31.0 34.0
0.5 28.7 6.0 26.4 7.0 4.9
1.0 10.1 6.7 4.8 1.9 7.8
2.0 1.6 1.3 0.8 1.3 1.9
>=4.0 3.9 0.7 . . 1.0
CLEVELAND <=0.03 5.3 8.9 9.2 5.5 25.6
0.06 5.3 17.9 9.2 9.6 .
0.125 6.2 39.8 30.8 28.8 20.5
0.25 14.2 26.0 30.0 43.8 41.0
0.5 54.0 6.5 18.3 11.0 12.8
1.0 10.6 0.8 0.8 . .
2.0 0.9 . 0.8 . .
>=4.0 3.5 . 0.8 1.4 .
COLUMBUS <=0.03 9.7 11.3 7.7 9.3 16.1
0.06 9.7 9.7 9.0 4.7 11.1
0.125 30.3 28.0 20.3 20.3 19.1
0.25 32.0 33.3 38.0 41.7 24.5
0.5 13.3 15.3 21.0 4.7 11.1
1.0 3.0 2.3 2.7 5.0 8.7
2.0 2.0 . 0.7 12.7 8.1
>=4.0 . . 0.7 1.7 1.3
DALLAS <=0.03 6.0 5.7 6.3 6.0 6.3
0.06 7.7 4.2 7.7 11.0 9.3
0.125 34.0 14.1 23.0 24.5 22.7
0.25 40.7 43.8 48.0 40.1 36.0
0.5 6.7 18.0 8.7 11.7 18.3
1.0 1.3 2.1 3.0 2.5 4.3
2.0 3.3 9.9 3.3 2.8 2.7
>=4.0 0.3 2.1 . 1.4 0.3
DENVER <=0.03 . . . . 3.2
0.06 . . . . 9.7
0.125 . . . . 23.4
0.25 . . . . 30.6
0.5 . . . . 27.4
1.0 . . . . 4.8
>=4.0 . . . . 0.8
GREENSBORO <=0.03 4.2 1.2 3.6 10.1 5.3
0.06 15.5 10.0 9.8 11.6 11.1
0.125 22.5 19.7 20.6 29.5 45.5
0.25 31.5 40.5 37.1 44.9 27.9
0.5 22.1 22.8 23.7 2.9 8.6
1.0 3.8 5.0 4.6 1.0 1.2
2.0 0.5 0.4 . . 0.4
>=4.0 . 0.4 0.5 . .
HONOLULU <=0.03 4.9 4.9 3.9 7.4 5.3
0.06 10.7 8.1 7.0 5.3 9.2
0.125 24.6 17.1 14.8 21.1 11.8
0.25 51.6 46.3 40.6 44.2 43.4
0.5 7.4 17.1 18.8 5.3 21.1
1.0 . 0.8 0.8 1.1 3.9
2.0 0.8 3.3 2.3 . 5.3
>=4.0 . 2.4 11.7 15.8 .
INDIANAPOLIS <=0.03 21.7 14.4 9.2 1.7 4.1
0.06 23.0 17.1 11.7 12.7 16.9
0.125 26.7 33.2 27.0 35.3 37.5
0.25 17.0 19.5 25.5 32.7 26.4
0.5 8.3 10.7 17.4 9.7 5.1
1.0 1.3 2.7 6.7 2.7 5.1
2.0 1.3 1.0 0.4 3.0 2.7
>=4.0 0.7 1.3 2.1 2.3 2.4
JACKSON 0.06 . . . . 4.8
0.125 . . . . 19.0
0.25 . . . . 28.6
0.5 . . . . 47.6
KANSAS CITY <=0.03 1.3 3.7 1.3 4.3 3.7
0.06 3.9 10.7 7.0 7.0 4.7
0.125 31.5 28.5 13.7 25.7 25.3
0.25 41.8 35.6 36.0 47.0 50.3
0.5 19.8 15.2 34.0 14.0 13.3
1.0 1.3 3.7 6.0 1.0 1.7
2.0 . 2.2 1.7 1.0 0.7
>=4.0 0.4 0.4 0.3 . 0.3
LAS VEGAS <=0.03 4.0 2.0 0.3 4.7 2.5
0.06 5.3 7.3 3.3 7.3 9.3
0.125 15.7 20.3 15.7 21.0 25.3
0.25 40.0 35.0 25.0 42.7 36.7
0.5 28.3 25.0 36.0 16.3 18.1
1.0 5.7 8.3 16.0 4.3 3.2
2.0 0.7 1.0 1.3 2.3 3.9
>=4.0 0.3 1.0 2.3 1.3 1.1
LOS ANGELES <=0.03 2.3 1.2 3.0 3.5 0.6
0.06 5.8 7.4 3.0 4.0 0.6
0.125 23.4 19.8 19.5 23.6 22.5
0.25 48.0 45.7 51.1 50.3 53.1
0.5 17.5 22.2 15.0 11.6 13.8
1.0 1.8 . 3.8 3.0 3.1
2.0 . 2.5 3.8 3.0 5.0
>=4.0 1.2 1.2 0.8 1.0 1.3
MIAMI 0.06 . . . . 5.3
0.125 . . . . 21.1
0.25 . . . . 52.6
0.5 . . . . 21.1
MILWAUKEE 0.06 . . . . 9.8
0.125 . . . . 17.1
0.25 . . . . 23.2
0.5 . . . . 36.6
1.0 . . . . 13.4
MINNEAPOLIS <=0.03 3.9 11.4 2.2 6.3 4.7
0.06 1.9 15.2 6.7 14.1 21.2
0.125 4.9 12.4 15.6 23.4 34.1
0.25 17.5 27.6 35.6 29.7 25.9
0.5 30.1 15.2 32.2 18.8 9.4
1.0 19.4 8.6 1.1 6.3 1.2
2.0 3.9 5.7 3.3 1.6 .
>=4.0 18.4 3.8 3.3 . 3.5
NEW ORLEANS <=0.03 2.9 1.5 . 3.6 2.4
0.06 5.3 5.3 1.9 8.7 14.6
0.125 9.4 26.7 18.6 17.4 19.5
0.25 32.2 29.8 21.1 46.4 42.3
0.5 35.7 25.2 37.9 18.1 13.0
1.0 9.9 9.9 18.0 3.6 4.9
2.0 4.7 0.8 1.2 1.4 3.3
>=4.0 . 0.8 1.2 0.7 .
NEW YORK CITY <=0.03 6.1 13.5 7.3 3.4 2.8
0.06 15.9 3.5 3.9 7.4 7.0
0.125 19.7 19.9 16.9 20.2 30.5
0.25 37.9 36.9 43.3 45.8 39.9
0.5 15.2 19.1 21.3 10.3 8.0
1.0 1.5 4.3 1.1 7.9 7.5
2.0 1.5 . 2.8 3.9 2.8
>=4.0 2.3 2.8 3.4 1.0 1.4
ORANGE COUNTY <=0.03 0.6 3.3 1.5 2.1 1.2
0.06 4.7 6.0 5.2 5.7 3.7
0.125 25.1 21.9 11.9 19.3 30.1
0.25 36.3 36.1 33.5 59.3 52.8
0.5 28.7 28.4 35.6 9.3 6.1
1.0 4.7 4.4 9.8 2.1 0.6
2.0 . . 1.0 2.1 4.3
>=4.0 . . 1.5 . 1.2
PHILADELPHIA <=0.03 2.3 1.3 1.3 4.6 14.0
0.06 8.7 5.7 5.3 4.6 6.0
0.125 18.0 22.0 14.3 19.1 17.7
0.25 35.3 34.3 23.7 39.6 27.7
0.5 28.7 29.0 38.0 14.5 13.0
1.0 4.7 6.3 11.7 5.3 9.3
2.0 . . 2.7 3.9 3.3
>=4.0 2.3 1.3 3.0 8.5 9.0
PHOENIX <=0.03 1.7 2.7 . 5.0 4.7
0.06 2.7 4.0 2.0 6.7 8.0
0.125 11.0 17.7 10.7 20.3 24.3
0.25 35.0 24.7 22.0 42.3 26.3
0.5 33.3 34.3 32.7 11.7 22.7
1.0 13.0 11.0 25.3 10.0 8.7
2.0 0.3 2.0 4.0 1.3 3.3
>=4.0 3.0 3.7 3.3 2.7 2.0
PONTIAC <=0.03 7.4 15.2 16.2 3.9 12.2
0.06 8.9 12.6 6.0 13.0 16.7
0.125 15.6 28.8 23.0 27.3 26.0
0.25 20.0 26.8 34.5 36.8 26.4
0.5 34.8 11.6 14.0 8.7 8.9
1.0 9.6 4.5 5.1 7.4 7.3
2.0 . 0.5 1.3 1.7 2.0
>=4.0 3.7 . . 1.3 0.4
PORTLAND <=0.03 3.1 2.0 3.4 6.7 3.2
0.06 4.7 8.1 5.4 5.9 4.8
0.125 21.1 14.9 15.0 22.7 23.4
0.25 52.3 56.8 59.9 52.1 48.4
0.5 14.1 13.5 7.5 5.0 8.9
1.0 . 0.7 2.0 1.7 4.8
2.0 0.8 3.4 6.8 4.2 3.2
>=4.0 3.9 0.7 . 1.7 3.2
SAN DIEGO <=0.03 2.8 2.6 . 4.6 2.7
0.06 4.1 5.3 3.6 2.1 3.4
0.125 15.6 22.2 9.8 14.9 24.5
0.25 37.2 30.2 28.5 65.6 49.7
0.5 32.6 33.9 34.7 9.2 8.2
1.0 7.8 5.3 21.8 2.6 4.1
2.0 . 0.5 1.6 0.5 7.5
>=4.0 . . . 0.5 .
SAN FRANCISCO <=0.03 0.3 2.7 3.3 2.3 2.9
0.06 4.7 6.0 5.7 6.0 2.1
0.125 27.0 20.7 20.0 25.7 21.9
0.25 53.7 48.3 53.7 45.3 38.8
0.5 11.7 19.0 11.0 12.7 11.6
1.0 1.7 1.7 0.7 2.7 11.2
2.0 0.3 1.3 4.0 4.7 9.9
>=4.0 0.7 0.3 1.7 0.7 1.7
SEATTLE <=0.03 5.2 3.2 0.5 2.8 1.8
0.06 2.1 1.6 6.4 2.4 0.4
0.125 14.4 17.1 26.1 19.1 16.1
0.25 57.2 48.7 42.0 49.6 60.7
0.5 12.9 20.3 16.5 13.8 6.7
1.0 3.6 4.3 2.7 8.1 8.5
2.0 1.0 2.1 4.3 3.7 4.9
>=4.0 3.6 2.7 1.6 0.4 0.9
TRIPLER <=0.03 10.0 27.3 . . 60.0
0.06 30.0 18.2 . . .
0.125 10.0 . 50.0 . .
0.25 10.0 36.4 50.0 . 40.0
0.5 30.0 18.2 . . .
2.0 10.0 . . . .
WASHINGTON DC <=0.03 . . . . 25.0
0.06 . . . . 25.0
0.25 . . . . 25.0
1.0 . . . . 25.0