Figure 31. Neisseria gonorrhoeae — Prevalence of Tetracycline, Penicillin, or Fluoroquinolone Resistance* or Elevated Cefixime, Ceftriaxone, or Azithromycin Minimum Inhibitory Concentrations (MICs)†, by Year — Gonococcal Isolate Surveillance Project (GISP), 2000–2017

Figure 31. Line graph showing prevalence of Tetracycline, Penicillin, or Fluoroquinolone Resistance or Elevated Cefixime, Ceftriaxone, or Azithromycin Minimum Inhibitory Concentrations (MICs) from 2000 to 2017 by Year. Data from the Gonococcal Isolate Surveillance Project.

* Resistance: Fluoroquinolone (ciprofloxacin) = MIC ≥1.0 µg/mL; Penicillin = MIC ≥2.0 µg/mL or B-lactamase positive; Tetracycline = MIC ≥2.0 µg/mL.

† Elevated MICs: Azithromycin = MIC ≥1.0 µg/mL (2000–2004); ≥2.0 µg/mL (2005–2017); Ceftriaxone = MIC ≥0.125 µg/mL; Cefixime = MIC ≥0.25 µg/mL.

NOTE: Cefixime susceptibility was not tested in 2007 and 2008.

ADAPTED FROM: Kirkcaldy RD, Harvey A, Papp JR, et al. Neisseria gonorrhoeae antimicrobial susceptibility surveillance — The Gonococcal Isolate Surveillance Project, 27 Sites, United States, 2014. MMWR Surveill Summ 2016; 65(7):1–24.

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