Table 15. Primary and Secondary Syphilis — Reported Cases and Rates of Reported Cases by Age Group and Sex, United States, 2016-2020

Table 15. Primary and Secondary Syphilis — Reported Cases and Rates of Reported Cases by Age Group and Sex, United States, 2016-2020
Year Age Group
Cases
Rates per 100,000 Population*
Total Male Female Unknown Sex Total Male Female
2016 0-4 2 0 2 0 0.0 0.0 0.0
5-9 2 1 1 0 0.0 0.0 0.0
10-14 15 6 9 0 0.1 0.1 0.1
15-19 1,298 957 340 1 6.1 8.9 3.3
20-24 5,172 4,418 744 10 23.1 38.4 6.8
25-29 6,177 5,538 624 15 27.0 47.6 5.5
30-34 4,278 3,806 464 8 19.6 34.7 4.3
35-39 3,043 2,729 311 3 14.6 26.3 3.0
40-44 2,140 1,944 193 3 10.9 19.9 1.9
45-54 3,953 3,691 261 1 9.2 17.5 1.2
55-64 1,418 1,338 80 0 3.4 6.7 0.4
65+ 279 269 10 0 0.6 1.2 0.0
Unknown Age 37 27 10 0
TOTAL 27,814 24,724 3,049 41 8.6 15.5 1.9
2017 0-4 5 0 5 0 0.0 0.0 0.1
5-9 1 0 1 0 0.0 0.0 0.0
10-14 20 6 14 0 0.1 0.1 0.1
15-19 1,421 1,092 327 2 6.7 10.1 3.2
20-24 5,580 4,728 848 4 25.2 41.7 7.9
25-29 6,838 6,033 795 10 29.3 50.7 6.9
30-34 4,870 4,313 549 8 22.2 38.9 5.0
35-39 3,580 3,145 431 4 16.9 29.6 4.1
40-44 2,290 2,005 282 3 11.7 20.6 2.9
45-54 4,091 3,753 334 4 9.7 18.0 1.6
55-64 1,586 1,468 117 1 3.8 7.2 0.5
65+ 349 329 19 1 0.7 1.5 0.1
Unknown Age 13 13 0 0
TOTAL 30,644 26,885 3,722 37 9.4 16.8 2.3
2018 0-4 2 1 1 0 0.0 0.0 0.0
5-9 0 0 0 0 0.0 0.0 0.0
10-14 20 9 11 0 0.1 0.1 0.1
15-19 1,618 1,175 442 1 7.7 10.9 4.3
20-24 6,140 5,061 1,076 3 28.1 45.2 10.1
25-29 7,712 6,625 1,077 10 32.7 55.1 9.3
30-34 5,907 5,084 816 7 26.7 45.4 7.5
35-39 4,200 3,574 621 5 19.5 33.1 5.8
40-44 2,690 2,328 358 4 13.6 23.8 3.6
45-54 4,398 3,973 423 2 10.6 19.3 2.0
55-64 1,929 1,782 145 2 4.6 8.7 0.7
65+ 437 412 25 0 0.8 1.8 0.1
Unknown Age 10 10 0 0
TOTAL 35,063 30,034 4,995 34 10.7 18.6 3.0
2019 0-4 5 4 1 0 0.0 0.0 0.0
5-9 2 1 1 0 0.0 0.0 0.0
10-14 22 9 13 0 0.1 0.1 0.1
15-19 1,708 1,202 502 4 8.1 11.2 4.9
20-24 6,325 5,064 1,234 27 29.2 45.8 11.7
25-29 8,308 6,924 1,361 23 35.3 57.7 11.8
30-34 6,829 5,725 1,085 19 30.4 50.4 9.8
35-39 4,837 3,987 839 11 22.3 36.6 7.7
40-44 3,276 2,689 579 8 16.4 27.1 5.8
45-54 4,749 4,099 646 4 11.6 20.3 3.1
55-64 2,412 2,210 201 1 5.7 10.8 0.9
65+ 515 485 30 0 1.0 2.0 0.1
Unknown Age 4 3 1 0
TOTAL 38,992 32,402 6,493 97 11.9 20.0 3.9
2020 0-4 1 1 0 0 0.0 0.0 0.0
5-9 2 2 0 0 0.0 0.0 0.0
10-14 24 8 16 0 0.1 0.1 0.2
15-19 1,782 1,166 612 4 8.5 10.9 5.9
20-24 6,351 4,817 1,512 22 29.4 43.5 14.3
25-29 8,659 6,975 1,651 33 36.8 58.1 14.4
30-34 7,779 6,319 1,439 21 34.7 55.7 13.0
35-39 5,284 4,289 983 12 24.3 39.4 9.1
40-44 3,693 2,963 727 3 18.5 29.9 7.3
45-54 4,936 4,227 702 7 12.1 21.0 3.4
55-64 2,544 2,333 208 3 6.0 11.4 0.9
65+ 548 505 40 3 1.0 2.1 0.1
Unknown Age 52 41 11 0
TOTAL 41,655 33,646 7,901 108 12.7 20.8 4.7
* No population data are available for unknown sex and age; therefore, rates are not calculated.

NOTE: The COVID-19 pandemic has introduced uncertainty and difficulty in interpreting 2020 case data. See Impact of COVID-19 on STDs for more information.

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