FIGURE I. PERCENTAGE OF ISOLATES WITH INTERMEDIATE RESISTANCE OR RESISTANCE TO CIPROFLOXACIN, 2000-2019
CLINIC | Percentage | ||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
2000 | 2001 | 2002 | 2003 | 2004 | 2005 | 2006 | 2007 | 2008 | 2009 | 2010 | 2011 | 2012 | 2013 | 2014 | 2015 | 2016 | 2017 | 2018 | 2019 | ||
Albuquerque | Intermediate Resistance | . | . | . | . | . | 5.7 | . | . | 2.0 | . | 4.8 | 5.3 | 5.3 | 3.6 | 3.5 | . | . | . | 0.5 | . |
Resistance | . | . | . | . | . | . | 7.3 | 16.7 | 6.9 | 7.3 | 22.9 | 21.7 | 16.4 | 15.1 | 6.1 | 9.6 | 15.7 | 22.6 | 12.4 | 29.4 | |
Anchorage | Intermediate Resistance | . | 1.9 | 3.7 | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Resistance | 6.9 | . | 3.7 | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | 52.9 | 50.8 | |
Baltimore | Intermediate Resistance | . | . | 0.3 | . | . | . | 0.7 | . | . | . | . | . | 0.3 | 1.0 | . | . | . | . | . | 2.0 |
Resistance | . | . | . | 0.3 | 1.0 | 3.0 | 1.4 | 2.0 | 5.4 | 5.1 | 10.2 | 1.7 | 5.3 | 19.3 | . | . | . | . | . | 41.6 | |
Birmingham | Intermediate Resistance | . | . | . | . | 0.3 | 0.3 | . | . | . | 1.0 | 3.8 | 10.8 | 3.7 | 6.5 | 0.4 | 2.3 | 5.8 | 11.4 | 4.1 | 1.0 |
Resistance | . | . | . | . | . | 1.0 | 1.1 | 9.4 | 8.3 | 10.0 | 10.9 | 17.9 | 14.7 | 8.5 | 15.7 | 15.4 | 16.4 | 23.6 | 25.5 | 36.9 | |
Buffalo | Intermediate Resistance | . | . | . | . | . | . | . | . | . | . | . | . | . | . | 1.1 | 1.4 | . | 0.7 | . | 1.5 |
Resistance | . | . | . | . | . | . | . | . | . | . | . | . | . | . | 14.9 | 21.4 | 38.3 | 15.4 | 14.7 | 37.3 | |
Camden | Intermediate Resistance | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | 2.3 |
Resistance | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | 43.2 | |
Chicago | Intermediate Resistance | 0.5 | . | 2.1 | 2.8 | 3.0 | 3.9 | 3.7 | 2.2 | 1.9 | 0.9 | . | 0.4 | 0.4 | . | 0.8 | 4.0 | 1.6 | 1.3 | . | . |
Resistance | . | . | . | 2.1 | 2.3 | 4.7 | 4.1 | 8.6 | 5.3 | 9.8 | 19.2 | 10.4 | 8.4 | 7.7 | 10.9 | 14.7 | 22.4 | 24.1 | 21.4 | 33.9 | |
Cleveland | Intermediate Resistance | 0.8 | . | 0.4 | 0.3 | 2.7 | 8.1 | 4.1 | 5.6 | 0.8 | 0.4 | . | . | . | 0.6 | 1.8 | 3.3 | 0.8 | . | 5.1 | 1.6 |
Resistance | . | . | . | 0.3 | 0.4 | 2.8 | 3.1 | 0.7 | 4.1 | 0.4 | 0.9 | 1.5 | 1.1 | 1.2 | 5.3 | 13.0 | 9.2 | 16.4 | 15.4 | 12.5 | |
Columbus | Intermediate Resistance | . | . | . | . | . | . | . | . | . | . | . | . | . | 2.3 | 0.3 | . | 0.7 | 0.7 | 0.3 | 1.0 |
Resistance | . | . | . | . | . | . | . | . | . | . | . | . | 7.1 | 3.3 | 5.3 | 15.7 | 21.7 | 27.0 | 29.5 | 38.0 | |
Dallas | Intermediate Resistance | 0.4 | . | . | . | 0.3 | 1.4 | 0.7 | . | . | 0.3 | 4.1 | 3.7 | 3.2 | 1.0 | 1.3 | 0.7 | 2.0 | 2.8 | 4.3 | 1.7 |
Resistance | . | . | . | 2.0 | 3.0 | 3.2 | 6.1 | 7.5 | 7.1 | 6.7 | 7.8 | 4.5 | 11.7 | 10.5 | 10.7 | 17.0 | 24.7 | 20.6 | 29.0 | 28.3 | |
Denver | Intermediate Resistance | . | . | . | 0.3 | . | . | . | . | 1.2 | 4.3 | 5.4 | 1.6 | 3.6 | 2.5 | . | . | . | . | 0.8 | 1.7 |
Resistance | . | 0.3 | . | 0.7 | 8.3 | 10.9 | 15.7 | 17.0 | 10.7 | 11.3 | 14.2 | 17.6 | 16.1 | 18.1 | . | . | . | . | 36.3 | 28.9 | |
Greensboro | Intermediate Resistance | . | . | . | . | . | 1.1 | . | . | . | . | . | . | . | . | . | 0.4 | 4.1 | 1.9 | 4.1 | 3.2 |
Resistance | . | . | . | . | 0.8 | 0.6 | 1.7 | 5.3 | 3.6 | 0.6 | 1.6 | 4.7 | 7.8 | 3.0 | 12.7 | 22.8 | 30.9 | 31.4 | 20.1 | 18.5 | |
Honolulu | Intermediate Resistance | 4.8 | 3.8 | 4.3 | 5.8 | . | 1.1 | 1.1 | 1.4 | . | . | . | 1.6 | 1.0 | . | . | . | 0.8 | . | 1.3 | . |
Resistance | 14.3 | 20.3 | 11.7 | 13.3 | 22.8 | 19.3 | 35.8 | 28.6 | 40.5 | 44.6 | 34.6 | 29.5 | 18.4 | 11.0 | 39.3 | 21.1 | 21.1 | 18.9 | 25.0 | 35.3 | |
Indianapolis | Intermediate Resistance | . | . | . | . | . | . | . | . | . | . | . | . | . | 0.7 | . | 0.3 | . | 1.3 | 2.7 | 2.0 |
Resistance | . | . | . | . | . | . | . | . | . | . | . | . | . | 11.0 | 12.3 | 14.8 | 11.0 | 13.7 | 18.2 | 23.5 | |
Jackson | Intermediate Resistance | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | 4.8 | . |
Resistance | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | 42.9 | 39.1 | |
Kansas City | Intermediate Resistance | . | . | . | . | . | . | . | 1.8 | 0.4 | . | . | 2.3 | 2.3 | 0.3 | 3.0 | 1.5 | 4.3 | 6.7 | 7.0 | 3.0 |
Resistance | . | . | . | . | . | . | . | 16.4 | 7.5 | 1.3 | 1.0 | 2.0 | 2.0 | 9.7 | 10.8 | 18.9 | 21.0 | 27.7 | 34.3 | 30.3 | |
Las Vegas | Intermediate Resistance | . | . | . | 0.3 | . | 0.7 | 1.0 | 1.3 | 1.7 | 1.0 | . | 1.0 | 3.2 | 1.7 | 2.0 | 1.3 | 0.7 | 1.7 | 3.9 | 2.0 |
Resistance | . | . | . | 2.4 | 2.4 | 5.4 | 8.7 | 18.7 | 17.7 | 11.0 | 7.7 | 8.9 | 19.8 | 27.3 | 17.0 | 25.3 | 28.3 | 32.7 | 34.2 | 36.2 | |
Los Angeles | Intermediate Resistance | . | . | . | 0.5 | 0.4 | . | . | 1.2 | . | . | 1.5 | . | 2.0 | . | . | . | 0.8 | 1.5 | 1.3 | 5.8 |
Resistance | . | . | . | 12.4 | 13.8 | 14.5 | 22.7 | 22.4 | 16.8 | 13.3 | 16.7 | 28.2 | 34.9 | 34.5 | 25.1 | 22.2 | 44.4 | 42.7 | 51.3 | 52.6 | |
Miami | Intermediate Resistance | . | 0.4 | 1.7 | 1.6 | 1.0 | 0.8 | 0.9 | 1.5 | 0.4 | . | 0.5 | 0.6 | 0.5 | 1.1 | . | . | . | . | . | . |
Resistance | . | . | 0.4 | 2.0 | 6.8 | 9.1 | 19.8 | 19.5 | 16.2 | 12.3 | 15.3 | 23.5 | 25.0 | 23.0 | . | . | . | . | 52.6 | 53.0 | |
Milwaukee | Resistance | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | 11.0 | 18.6 |
Minneapolis | Intermediate Resistance | 0.3 | . | . | . | 0.8 | . | 0.4 | . | . | . | . | 4.3 | . | . | 2.9 | 3.8 | 2.2 | . | . | . |
Resistance | . | . | 0.5 | 2.3 | 9.3 | 8.0 | 5.7 | 10.7 | 7.6 | 24.4 | 23.9 | 23.4 | 11.5 | 17.5 | 20.4 | 37.1 | 31.1 | 28.1 | 27.1 | 38.6 | |
New Orleans | Intermediate Resistance | . | 0.8 | . | . | . | . | . | 0.4 | . | . | 2.1 | 2.0 | 4.9 | 7.2 | 2.3 | . | 1.2 | 0.7 | 1.6 | 0.8 |
Resistance | 0.4 | . | . | 0.4 | 1.5 | 6.3 | 10.2 | 18.1 | 14.9 | 7.9 | 12.8 | 11.3 | 9.4 | 12.0 | 12.9 | 20.6 | 24.8 | 27.5 | 35.8 | 33.9 | |
New York City | Intermediate Resistance | . | . | . | . | . | . | . | 1.1 | 4.1 | . | 0.5 | . | 1.6 | . | . | 2.1 | . | 1.5 | 0.5 | 1.2 |
Resistance | . | . | . | . | . | . | 7.5 | 14.9 | 15.4 | 15.6 | 13.6 | 16.7 | 9.8 | 17.7 | 23.5 | 34.0 | 34.8 | 42.9 | 42.3 | 41.4 | |
Orange County | Intermediate Resistance | . | 1.6 | 0.6 | 0.6 | 1.9 | 1.7 | 0.8 | . | . | . | 1.0 | 5.6 | 1.6 | 0.8 | 1.2 | 0.5 | 1.0 | . | . | 3.8 |
Resistance | 5.6 | 2.3 | 11.4 | 31.5 | 20.5 | 27.5 | 34.6 | 41.0 | 33.3 | 18.3 | 23.1 | 25.2 | 33.9 | 44.4 | 30.4 | 29.0 | 38.1 | 44.3 | 46.6 | 53.8 | |
Philadelphia | Intermediate Resistance | 0.3 | 0.3 | . | 0.3 | 0.3 | . | . | . | . | 0.5 | 0.7 | . | . | 0.7 | 1.0 | 0.7 | 0.7 | 1.1 | 1.0 | 1.7 |
Resistance | . | . | 1.0 | 1.3 | 3.3 | 14.3 | 30.3 | 29.1 | 20.6 | 15.5 | 13.9 | 7.6 | 20.3 | 14.0 | 23.0 | 25.3 | 21.7 | 37.5 | 38.7 | 53.0 | |
Phoenix | Intermediate Resistance | 3.4 | 2.1 | . | 0.4 | 0.3 | 0.4 | 0.4 | . | . | . | 0.5 | 0.7 | 2.0 | . | . | 0.7 | 1.0 | 0.3 | 1.7 | 1.0 |
Resistance | . | . | 0.3 | 2.6 | 6.6 | 7.1 | 11.9 | 8.7 | 16.5 | 15.9 | 15.6 | 10.7 | 10.7 | 13.0 | 21.0 | 28.7 | 28.0 | 20.0 | 23.3 | 31.7 | |
Pontiac | Intermediate Resistance | . | . | . | . | . | . | . | . | . | . | . | . | . | 0.5 | 3.0 | 2.0 | . | 0.4 | 1.2 | 1.0 |
Resistance | . | . | . | . | . | . | . | . | . | . | . | . | 3.1 | 6.3 | 11.1 | 13.6 | 25.1 | 24.7 | 26.4 | 25.8 | |
Portland | Intermediate Resistance | 2.0 | 2.1 | 2.6 | 3.0 | 0.5 | . | 1.8 | . | . | . | . | 0.6 | 0.9 | . | . | 1.4 | . | 0.8 | . | . |
Resistance | . | . | 1.7 | 3.0 | 11.5 | 23.1 | 27.2 | 28.6 | 51.6 | 20.0 | 25.5 | 24.0 | 20.9 | 14.7 | 37.5 | 34.5 | 47.6 | 38.7 | 22.6 | 19.0 | |
San Diego | Intermediate Resistance | 0.4 | 1.7 | 1.2 | 1.6 | 0.8 | 0.7 | 1.5 | 1.6 | . | 0.6 | 2.4 | 4.8 | 3.9 | 3.4 | 2.8 | 1.1 | 1.0 | 1.5 | 2.0 | 3.0 |
Resistance | 0.4 | 2.1 | 16.5 | 13.2 | 20.6 | 26.2 | 35.1 | 36.3 | 29.1 | 20.9 | 20.0 | 31.4 | 38.5 | 31.8 | 30.3 | 31.2 | 40.4 | 55.9 | 49.0 | 59.4 | |
San Francisco | Intermediate Resistance | 9.9 | 17.2 | 9.9 | 3.6 | 4.0 | 3.0 | . | . | 0.5 | 0.8 | 1.7 | 0.9 | 1.2 | . | 0.3 | 4.3 | 0.7 | 1.3 | 0.8 | 1.2 |
Resistance | 0.3 | 3.4 | 6.7 | 19.2 | 24.3 | 31.3 | 44.5 | 31.3 | 26.1 | 10.0 | 18.3 | 32.1 | 32.9 | 34.9 | 33.0 | 30.0 | 29.3 | 40.0 | 41.7 | 42.6 | |
Seattle | Intermediate Resistance | 2.3 | 2.8 | 3.7 | 3.5 | 3.4 | 0.4 | 13.2 | 19.1 | 14.1 | 4.9 | 0.4 | 1.2 | . | . | . | . | 1.1 | 0.8 | 0.9 | 2.2 |
Resistance | 0.9 | . | 3.0 | 7.0 | 16.2 | 11.6 | 31.8 | 29.3 | 31.3 | 21.0 | 47.9 | 41.9 | 32.2 | 44.1 | 38.1 | 27.8 | 29.3 | 32.5 | 43.8 | 43.7 | |
Tripler | Resistance | . | . | . | 4.2 | 28.6 | . | . | . | . | 16.7 | . | . | . | 36.4 | 30.0 | 9.1 | 50.0 | . | 40.0 | 33.3 |
Washington, D.C. |
Intermediate Resistance | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | 5.2 |
Resistance | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | 50.0 | 41.6 |