Congenital Syphilis — Reported Cases by Vital Status and Clinical Signs and Symptoms* of Infection, United States, 2015–2019

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Area plot showing number of cases of congenital syphilis by vital status and clinical signs and symptoms of infection in the United States from 2015 to 2019.

*Infants with signs/symptoms of congenital syphilis have documentation of at least one of the following: long bone changes consistent with congenital syphilis, snuffles, condyloma lata, syphilitic skin rash, pseudoparalysis, hepatosplenomegaly, edema, jaundice due to syphilitic hepatitis, reactive CSF-VDRL, elevated CSF WBC or protein, or evidence of direct detection of T. Pallidum.

NOTE: Of the 5,269 congenital syphilis cases reported during 2015–2019, 22 (0.4%) did not have sufficient information to be categorized

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Page last reviewed: April 13, 2021
Content source: Division of STD Prevention, National Center for HIV, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention