Congenital Syphilis — Reported Cases by Vital Status and Clinical Signs and Symptoms* of Infection, United States, 2015–2019

Area plot showing number of cases of congenital syphilis by vital status and clinical signs and symptoms of infection in the United States from 2015 to 2019.

*Infants with signs/symptoms of congenital syphilis have documentation of at least one of the following: long bone changes consistent with congenital syphilis, snuffles, condyloma lata, syphilitic skin rash, pseudoparalysis, hepatosplenomegaly, edema, jaundice due to syphilitic hepatitis, reactive CSF-VDRL, elevated CSF WBC or protein, or evidence of direct detection of T. Pallidum.

NOTE: Of the 5,269 congenital syphilis cases reported during 2015–2019, 22 (0.4%) did not have sufficient information to be categorized