Investigation Update: Multistate Outbreak of Human Salmonella Enteritidis Infections Associated with Shell Eggs

Number of Salmonella Enteritidis cases matching PFGE pattern JEGX01.0004 reported to PulseNet, United States, 2010

In early July 2010, CDC identified a nationwide sustained increase in the number of Salmonella Enteritidis isolates with PFGE pattern JEGX01.0004 uploaded to PulseNet, the national subtyping network made up of state and local public health laboratories and federal food regulatory laboratories that performs molecular surveillance of foodborne infections. This increase began in May 2010, and is evident in the epidemic curve, or epi curve. From May 1 to August 25, 2010, a total of 2,403 illnesses were reported. However, some cases from this time period have not been reported yet, and some of these cases may not be related to this outbreak. Based on the previous 5 years of reports to PulseNet, we would expect approximately 933 total illnesses during this same period. This means that there are approximately 1,470 reported illnesses that are likely to be associated with this outbreak. Many states have reported increases of this pattern since May. Because of the large number of expected cases during this period, standard methods of molecular subtyping alone are not sufficient to determine which reported cases might be outbreak-associated. CDC is currently conducting testing using advanced molecular methodologies to help distinguish between outbreak-related cases and sporadic (or background) cases.

Illnesses that occurred after July 23, 2010 might not yet be reported due to the time it takes between when a person becomes ill and when the illness is reported. This takes an average of 2 to 3 weeks for Salmonella. For more details, please see the Salmonella Outbreak Investigations: Timeline for Reporting Cases.