Appendix E: Management of Women with Bleeding Irregularities While Using Contraception*

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If bleeding persists, or if the woman requests it, medical treatment can be considered.

Cu-IUD users

LNG-IUD users

Implant users

Injectable (DMPA) users

CHC users (extended or continuous regimen)

For unscheduled spotting or light bleeding or for heavy or prolonged bleeding: NSAIDs (5-7 days of treatment)

For unscheduled spotting or light bleeding or for heavy or prolonged bleeding:

– NSAIDs (5-7 days of treatment)

– Hormonal treatment (if medically eligible) with COCs or estrogen (10-20 days of treatment)

For unscheduled spotting or light bleeding: NSAIDs (5-7 days of treatment)

For heavy or prolonged bleeding:

– NSAIDs (5-7 days of treatment)

– Hormonal treatment (if medically eligible) with COCs or estrogen (10-20 days of treatment)

Hormone-free interval for 3-4 consecutive days

Not recommended during the first 21 days of extended or continuous CHC use

Not recommended more than once per month because contraceptive effectiveness might be reduced

If bleeding disorder persists or woman finds it unacceptable

Counsel on alternative methods and offer another method, if desired.

Cu-IUD users

For unscheduled spotting or light bleeding or for heavy or prolonged bleeding: NSAIDs (5-7 days of treatment)

If bleeding disorder persists or woman finds it unacceptable

Counsel on alternative methods and offer another method, if desired.

LNG-IUD users

If bleeding disorder persists or woman finds it unacceptable

Counsel on alternative methods and offer another method, if desired.

Implant users

For unscheduled spotting or light bleeding or for heavy or prolonged bleeding:

– NSAIDs (5-7 days of treatment)

– Hormonal treatment (if medically eligible) with COCs or estrogen (10-20 days of treatment)

If bleeding disorder persists or woman finds it unacceptable

Counsel on alternative methods and offer another method, if desired.

Injectable (DMPA) users

For unscheduled spotting or light bleeding: NSAIDs (5-7 days of treatment)

For heavy or prolonged bleeding:

– NSAIDs (5-7 days of treatment)

– Hormonal treatment (if medically eligible) with COCs or estrogen (10-20 days of treatment)

If bleeding disorder persists or woman finds it unacceptable

Counsel on alternative methods and offer another method, if desired.

CHC users (extended or continuous regimen)

Hormone-free interval for 3-4 consecutive days

Not recommended during the first 21 days of extended or continuous CHC use

Not recommended more than once per month because contraceptive effectiveness might be reduced

If bleeding disorder persists or woman finds it unacceptable

Counsel on alternative methods and offer another method, if desired.

Abbreviations: CHC = combined hormonal contraceptive; COC = combined oral contraceptive; Cu-IUD = copper-containing intrauterine device; DMPA = depot medroxyprogesterone acetate; LNG-IUD = levonorgestrel-releasing intrauterine device; NSAIDs = nonsteroidal antiinflammatory drugs.

*If clinically warranted, evaluate for underlying condition. Treat the condition or refer for care. Heavy or prolonged bleeding, either unscheduled or menstrual, is uncommon among LNG-IUD users and implant users.

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