Vaccine and Immune Globulin Availability

Rabies Vaccine

RabAvertexternal icon rabies vaccine (produced by Bavarian Nordic) is available with no restrictions.
IMOVAXexternal icon rabies vaccine (produced by Sanofi Pasteur) is available from wholesalers, distributors, and directly from the manufacturer. Call Sanofi Pasteur at 1-800-VACCINE if IMOVAX is not available from your wholesaler or distributor.

Human Rabies Immune Globulin

KEDRABexternal icon (produced by Kedrion Biopharma) is available with no restrictions.
HyperRabexternal icon (produced by Grifols) is available with no restrictions. (HyperRab® is a more potent version of the previously licensed HyperRab™ S/Dexternal icon and requires a smaller volume to achieve the recommended 20 IU/kg dose.)
Imogamexternal icon (produced by Sanofi Pasteur) is available with no restrictions.

*Note: HyperRab®external icon immunoglobulin product has a different concentration compared to all other rabies immunoglobulin products (including the very similarly named HyperRab™external icon S/D) and requires lower volumes to administer the recommended dose of 20 IU/kg. Care should be taken to ensure the correct dose of immunoglobulin is administered to ensure adequate immune response.

Recommended Preventive Measures

Standard rabies exposure prevention messaging should be reinforced.
- Pets and livestock should be vaccinated against rabies as recommended.
- When possible, after an exposure, efforts should be made to safely capture the animal involved in the exposure and it should be held for observation (if a cat, dog, or ferret) or tested for rabies.
Health providers should consult with local/state public health departments to ensure appropriate use of PEP. See: State and local rabies consultation contacts
Persons at increased risk for rabies exposure should take appropriate precautions to avoid exposure and consider rabies pre-exposure prophylaxis according to ACIP recommendations.

Disclaimer

Use of trade names and commercial sources is for identification only and does not imply endorsement by the U.S. Department of Health and Human Services.

Page last reviewed: August 24, 2020

Content source: Centers for Disease Control and Prevention, National Center for Emerging and Zoonotic Infectious Diseases (NCEZID), Division of High-Consequence Pathogens and Pathology (DHCPP)