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Note to visitors: Resources included in this web site contain terminology used at the time of publication and may not reflect current terms.

Injection drug use is a well-known route of transmission of blood borne infections, particularly HIV and hepatitis B and C. Use of illicit drugs is associated with increased rates of TB and STDs. This web site provides materials and resources to assist researchers, policymakers, and clinical and program providers who work with persons who use drugs (PWUD), their sex partners and families. This site does not address issues related to the use of cannabinoids or licit drugs, such as alcohol, or tobacco.

Data and Statistics

Estimated New Infections among People Who Inject Drugs by Gender and Race/Ethnicity, 2010—United States*

Bar chart showing new HIV infections for male and female injection drug users by race/ethnicity for 2010., full details at

Visit CDC’s HIV Risk & Prevention: Injection Drug Use page for more information.

Guidance and Interventions

Person in blue scrubs holding a heart-shapped stress ball in hands.

Strategies for Disease Prevention
Includes Behavioral Interventions, Outreach, Safe Syringe Practices, Testing and Vaccines, Drug Poisoning and Overdose Prevention, and Integrated Guidelines

Two women sitting on couches and having a conversation as if one is being counseled

Substance Abuse Treatment
Focuses on substance abuse treatment and disease prevention


Clinician examining a patient's neck

Disease Treatment for Persons at Risk
Includes medical interventions to prevent and treat infectious disease

pills spelling out the word help

Assistance for Persons Who Use Drugs

Find services near you for:

  • Substance Abuse and/or Mental Health Treatment Facility Locator
  • Buprenorphine Physicians & Treatment Program
  • Opioid Treatment

Call SAMHSA’s Referral Helpline 24/7 at 1-800-662-HELP (1-800-662-4357)