Signs and Symptoms

2022 U.S. Monkeypox Cases
  • CDC is tracking multiple cases of monkeypox that have been reported in several countries that don’t normally report monkeypox, including the United States.
  • CDC is urging healthcare providers in the U.S. to be alert for patients who have rash illnesses consistent with monkeypox.
  • CDC is working with state and local health officials to identify people who may have been in contact with individuals who have tested positive for monkeypox, so they can monitor their health.
  • Monkeypox is rare and does not spread easily between people without close contact. The threat of monkeypox to the general U.S. population remains LOW.

Monkeypox is a rare disease caused by infection with the monkeypox virus. Monkeypox virus is part of the same family of viruses as smallpox. Monkeypox symptoms are similar to smallpox symptoms, but milder; and monkeypox is rarely fatal. Monkeypox is not related to chickenpox.

Symptoms of monkeypox can include:

  • Fever
  • Headache
  • Muscle aches and backache
  • Swollen lymph nodes
  • Chills
  • Exhaustion
  • A rash that can look like pimples or blisters that appears on the face, inside the mouth, and on other parts of the body, like the hands, feet, chest, genitals, or anus.
    • The rash goes through different stages before healing completely. The illness typically lasts 2-4 weeks.

Sometimes, people get a rash first, followed by other symptoms. Others only experience a rash.

Examples of Monkeypox Rashes
Photo Credit: NHS England High Consequence Infectious Diseases Network
MonkeyPox Rash Collage
More Monkeypox Rash Photos
Photo credit: UK Health Security Agency
6 images of lesions to help identify monkeypox rash