CDC is updating webpages with the term "mpox" to reduce stigma and other issues associated with prior terminology. This change is aligned with the recent World Health Organization decision.

Mpox Vaccine Information for Healthcare Professionals

UpdatedInterim Clinical Considerations for Mpox Vaccination

When properly administered before an exposure, vaccines are effective at protecting people against mpox. Experts also believe that vaccination after an mpox exposure may help prevent the disease or make it less severe.

JYNNEOS™ and ACAM2000® are the two vaccines that may be used for the prevention of mpox disease.

Vaccine Considerations
Provider Agreement for Mpox Vaccination Program

Requirements and recommendations for JYNNEOS™ and ACAM2000® vaccine providers participating in the HHS Mpox Vaccination Program.