Global Activities

Diseases can spread around the world very quickly, so it’s important for CDC’s One Health Office to work closely with other countries to build strong partnerships with human, animal, and environmental health organizations. This protects Americans from illnesses that cross borders and affect travelers.

Prioritizing Zoonotic Diseases Using a One Health Approach

CDC’s One Health experts are working globally to implement a One Health Zoonotic Disease Prioritization process that builds collaboration across disciplines and sectors to focus limited resources on preventing, detecting, and responding to those zoonotic diseases of greatest national concern.

Learn more about the One Health Zoonotic Disease Prioritization process.

Global Health Security Agenda

The Global Health Security Agendaexternal icon (GHSA) is an effort by nations, international organizations, and civil society to accelerate progress toward a world safe and secure from infectious disease threats; to promote global health security as an international priority; and to spur progress toward full implementation of the World Health Organizationexternal icon (WHO) International Health Regulationsexternal icon 2005 (IHR), the World Organization for Animal Healthexternal icon (OIE) Performance of Veterinary Services (PVS) pathwayexternal icon, and other relevant global health security frameworks.

In order to encourage progress toward these goals, the “Action Packages” concept was developed to facilitate regional and global collaboration toward specific GHSA objectives and targets. All countries that support the GHSA are welcome to participate in one or more Action Packages and are asked to consider specific commitments across these areas on a national, regional, or global basis.

A One Health approach is used in several of the Action Packages, including the Zoonotic Disease Action Package. The CDC One Health Zoonotic Disease Prioritization Workshop can help countries identify the five zoonotic diseases/pathogens of greatest public health concern using a multisectoral, One Health approach to meet GHSA targets.

Animal-Human Interface Officers in CDC Global Disease Detection Sites

CDC’s Animal-Human Interface (AHI) Officers work with partners in CDC Global Disease Detection (GDD) sites in various countries—including Kenya, Bangladesh, and others—to help promote and conduct One Health work. The Global Disease Detection program (GDD) promotes scientific discovery by partnering with host countries to identify new health threats and reduce the burden of infectious diseases. GDD is CDC’s principal program for advancing the science behind global health security. With over a decade of experience between SARS and Ebola — and over 1700 outbreaks and public health emergencies responded to – the GDD program is critical to helping countries meet their commitments to the International Health Regulations and the Global Health Security Agendaexternal icon.

GDD has supported over 50 countries through its 10 Centers worldwide. Centers work with countries to build and strengthen public health capacity. They do this through:

  • Detecting and responding to emerging infectious diseases.
  • Developing a global workforce.
  • Enhancing laboratory systems.
  • Increasing preparedness and communication activities.
  • Addressing the animal and human interface responsible for zoonotic infections.
  • Conducting public health research.

Learn more about GDD Centers.

World Organisation for Animal Health (OIE) Collaborating Center for Emerging and Reemerging Zoonotic Diseases

CDC is a World Organisation for Animal Health (OIE) Collaborating Centerexternal icon for Emerging and Reemerging Zoonotic Diseases. Annual Reports of the OIE Collaborating Centersexternal icon are available.


CDC scientists study how diseases in animals become threats to human health in the United States and around the world. They also look at how changes in the environment affect the health of animals and humans. Their research helps us understand:

  • How viruses, bacteria, parasites, and fungi spread between animals and humans.
  • How a person’s behavior can increase the risk that they will get sick from an animal.
  • How quickly these diseases can spread.
Global map

Collaboration and Partnerships

In many countries, CDC works with local and national governments as well as animal, environmental, and human health partners. CDC also works with international organizations. These include: