National Occupational Research Agenda for Cancer, Reproductive, Cardiovascular and Other Chronic Disease Prevention (CRC)

The Cancer, Reproductive, Cardiovascular, and Other Chronic Disease Prevention (CRC) Cross-Sector developed strategic objectives for research based on, to the greatest extent possible, basic public health criteria such as number/prevalence of workers affected and severity. This Agenda was developed as a product of a series of meetings of the NORA CRC Cross-Sector Council in 2017. The Agenda is based on information from the scientific literature, individual expertise and experience, and discussion within and among the CRC Council members. The 12 objectives in the Agenda focus on occupational cancer, adverse reproductive outcomes related to occupation, and cardiovascular disease among workers. The Agenda currently contains no objectives for neurologic and renal diseases among workers. The CRC Council finalized this version of the Agenda after considering public comments on the previous draft.

National Occupational Research Agenda for CRC


Objective 1: Improve the ability to assess the burden associated with occupational cancer.

Objective 2: Assess the magnitude and characteristics of worker exposures and associated control technologies.

Objective 3: Conduct analytic epidemiology and toxicology studies of prioritized populations and exposures to identify (or rule out) potential occupational carcinogens.

Objective 4: Develop laboratory-based research.

Objective 5: Perform research to investigate the effectiveness of workplace screening for early detection of occupational cancers.

Objective 6: Develop new methods for and conduct quantitative cancer risk assessments in support of authoritative recommendations for preventing occupational cancers.

Adverse Reproductive Outcomes

Objective 7: Improve understanding of mechanisms by which hazardous agents and workplace factors are related to adverse reproductive outcomes.

Objective 8: Improve the efficiency and effectiveness of systems to identify adverse reproductive outcomes, potential workplace risk factors and workers at risk.

Objective 9: Conduct and communicate studies of exposure and outcome; identify and quantify risk of adverse reproductive health outcomes associated with the workplace.

Cardiovascular Disease (CVD)

Objective 10: Understand underlying mechanisms for CVD among workers.

Objective 11: Understand risk factors associated with CVD.

Objective 12: Develop and evaluate workplace interventions for CVD.

Page last reviewed: November 28, 2017