NMI Notes

NMI Notes

Overall Updates



  • The next NNDSS eSHARE session is scheduled for Tuesday, 3/16/21, from 3:00 to 4:00 PM ET. The March eSHARE topic will be:
    • Implementing STD and Congenital Syphilis HL7 Case Notification Messages
    • Obtaining SAMS Access for MVPS Portal Data Managers and Users.
  • Access past eSHARE presentations at the NNDSS eSHARE website.

COVID-19 Vaccination Information

  • CDC encourages jurisdictions to send vaccine history information in coronavirus disease 2019 (COVID-19) case notifications using these options:
  • Full COVID-19 message mapping guide (MMG),
  • COVID Lite (generic v2 MMG plus vaccine history from COVID-19 MMG), or
  • DCIPHER/HHS Protect CSV upload using the updated January 2021 CSV template.
  • Find resources at the NNDSS Technical Resource Center.

COVID-19 Value Sets Updated

Core Requested Data Elements for COVID-19

  • As resources allow, jurisdictions are encouraged to send additional case information through the CSV upload to DCIPHER or through the COVID-19 MMG.

NNDSS Annual Data Reconciliation

  • 2019 Data:
    • CDC closed the NNDSS database for updates to 2019 data on 12/10/20.
  • 2020 Data:
    • CDC recognizes the demands of the pandemic on jurisdictions and CDC resources; therefore, the timeline for the reconciliation of the 2020 data is delayed, compared to a non-pandemic year.
    • Data reconciliation will be done using the Message Validation, Processing, and Provisioning System (MVPS) Portal.
      • Jurisdictions will view and extract the line list and aggregate tables from MVPS for all NNDSS case notification methods (HL7, National Electronic Telecommunications System for Surveillance [NETSS], NEDSS Base System [NBS] master message).
      • Jurisdictions can work at their own pace (but must still meet the established deadline).
      • State Epidemiologist sign-off process will be in MVPS.
    • Timeline:
      • June 2021: Jurisdictions receive training and have access to line lists and aggregate tables in MVPS.
      • September 30, 2021: Jurisdiction deadline for sign-off on final data.

Join a Cohort to Jumpstart Your MMG Implementations!

  • The NNDSS Association of Public Health Laboratories Technical Assistance team provides technical assistance to help groups, or cohorts, of public health agencies build and implement NNDSS HL7 case notification messages.
  • Cohorts of 4–6 public health agencies focusing on the generic v2 and the COVID MMGs have been established.
  • APHL and NBS subject matter experts guide participants through planning, gap analysis, data extraction, HL7 message creation, and validation. At completion, public health agencies will be ready to begin onboarding.
  • For those interested in joining a cohort, please email the CDC Electronic Data Exchange mailbox at edx@cdc.gov.

Production HL7 Case Notification Messages

MMGs in Production

Arboviral v1.3


Congenital Syphilis and STD

  • CDC posted new versions of the guides, which include new data elements and updated value sets, to the NNDSS Technical Resource Center.
    • Jurisdictions implementing previous versions of the guides will be allowed to onboard with them.
    • Jurisdictions who have not yet implemented the STD or CS guides should use the newly released versions.
  • CDC distributed an email on 2/25/21 through edx@cdc.gov that announced that the new STD and CS guides are open for general onboarding and included specific guide updates and guidance from the STD program on implementation of these guides. Please find details in this announcement.

Coronavirus Disease 2019

  • MMG and Data Elements
    • The MMG and artifacts are available on the NNDSS Technical Resource Center.
    • Due to the evolving nature of COVID-19 vaccines and lab testing, the value sets that are affected will be updated regularly.
      • The COVID-19 case notification vocabulary view in the PHIN Vocabulary Access and Distribution System (PHIN VADS) will be updated routinely to reflect these changes.
  • Onboarding
    • The COVID-19 MMG is open for onboarding, and the first cohort has begun onboarding. For those interested in implementing the COVID-19 MMG, please email edx@cdc.gov.

Foodborne and Diarrheal Diseases 

Generic v2

Healthcare-Associated Infections, Multi-Drug Resistant Organisms (HAI MDRO)


Lyme and Tickborne Rickettsial Diseases (TBRD)


Mumps and Pertussis

Respiratory Invasive Bacterial Disease


Tuberculosis and Latent Tuberculosis Infection


Developing HL7 Case Notification Messages

Developing HL7 Case Notification Messages

Bacterial Special Pathogens (Stage I—Draft)

  • Prioritization of response activities has delayed the external review comment period to gather jurisdiction feedback.
  • CDC expects to post the four MMGs (anthrax, brucellosis, Hansen’s disease, and leptospirosis) for external review in mid-2021.

Carbon Monoxide Poisoning (Stage II—Pilot Test-ready)

  • The pilot start date has been postponed.

Lead Poisoning (Requirements Analysis)

  • No new updates at this time.

Listeriosis (Stage I—Draft)

  • No new updates at this time.

Measles (Stage III—Final MMG)

Rubella and Congenital Rubella Syndrome (Stage III—Final MMG)



Jurisdiction Implementation of NNDSS HL7 Case Notification Messages

This chart shows the status of state public health departments who are piloting, receiving technical assistance, onboarding, or in production for HL7 case notification messages developed as part of the NNDSS Modernization Initiative.

Upcoming Events


NMI Notes provides monthly news updates about the National Notifiable Diseases Surveillance System (NNDSS) Modernization Initiative (NMI). It is a collaboration by the Centers for Disease Control and Prevention (CDC), Council of State and Territorial Epidemiologists (CSTE), and Association of Public Health Laboratories (APHL).

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Centers for Disease Control and Prevention | Council of State and Territorial Epidemiologists |
Association of Public Health Laboratories

Write: edx@cdc.gov        Visit: www.cdc.gov/nndss/

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