NMI Notes

NMI Notes

Overall Updates

NNDSS - National Notifiable Diseases Surveillance System

CSTE Approved an Interim Position Statement for COVID-19

 NNDSS Annual Reconciliation Postponed by Four Months

  • The annual reconciliation of 2019 NNDSS data will be postponed by four months to allow states and CDC program staff to focus on the COVID-19 response.
  • The new dates are shown in the table below.
  • Please feel free to reach out to the Data Operations Team if you have any questions or concerns.
Revised Dates for Reconciliation of 2019 NNDSS Data
New Dates Activity
Aug 28, 2020 Last day for jurisdiction to send 2019 data in weekly NETSS transmissions
Sep 25, 2020 ArborNet database closed
Sep 30, 2020 STD database closed
Sep 30, 2020 Ped Flu and Novel Flu database closed
Sep 30, 2020 Rabies, animal and human database closed
Sep 30, 2020 Varicella morbidity and mortality database closed
Sep 30, 2020 Last date for jurisdictions to transmit/update the 2019 FINAL data
Oct 16, 2020 Distribution of final counts to State Epidemiologists for signatures
Oct 30, 2020 Last date for State/Territorial Epidemiologists to return approved counts
Oct 30, 2020 Finalized 2019 NNDSS database closed at CDC
Mar 12, 2021 Publication of 2019 NNDSS Annual Tables

Reporting of COVID-19 through NNDSS:

  • Jurisdictions can now initiate COVID-19 reports through NNDSS and provide supplemental information through an upload or direct entry to DCIPHER. Please see the guidance provided by the CDC EOC on 4/7/20 for details. (You may email edx@cdc.gov for a copy.)
  • We encourage jurisdictions to send COVID-19 case notifications in NNDSS and would like to have complete counts in NNDSS when the 2020 data reconciliation is complete.
  • Please use event code 11065 for COVID-19 cases submitted through NNDSS.
  • To support linkage of NNDSS case notifications to data collected through the other methods:
    • Please include CDC COVID-19 case identifier in comment field in case notifications.
    • Please include the HL7 Local Record ID (OBR-3) or the National Electronic Telecommunications System for Surveillance (NETSS) Case ID on all supplemental information provided to CDC.
  • We encourage you to transmit more often than once a week to provide up-to-date information.
  • Please contact the CDC Electronic Data Exchange mailbox at edx@cdc.gov for technical support and with any questions.

 Target Date for Transition to New TB/LTBI Case Notification Message Extended

  • Given the current coronavirus situation, the Division of Tuberculosis Elimination (DTBE) has extended the deadline for cooperative agreement funding recipients to transition to the new tuberculosis (TB) and latent TB infection (LTBI) case notification message.
  • Jurisdictions are now expected to complete the transition by the end of 2021 rather than the end of 2020.
  • The TB Program remains ready to assist any jurisdiction that wants to work on the new TB/LTBI message at any time.

SAMS NETSS Secure File Transfer Migrated to SAMS Secure Data eXchange:

  • Jurisdiction users who deliver NETSS files via CDC Secure Access Management Services (SAMS) must now upload their NETSS files through SAMS Secure Data eXchange (SAMS SDX).
  • CDC emailed documentation on the new upload process to NETSS senders in March. This documentation also is available on the NNDSS website under Downloads and Resources.
  • See the 3/17/2020 and 2/18/20 eSHARE presentations and webinar recordings in the NMI eSHARE archives for  more information about this change.
  • Please contact edx@cdc.gov with questions.

 Additional Guides Expected to Open for Onboarding in 2020

  • CDC opened the sexually transmitted diseases (STD) and congenital syphilis (CS) MMGs for onboarding in January, starting with a few jurisdictions that had already completed preparation work. Watch for an email with additional information, including guidance from the STD program on implementation of these guides.
  • CDC opened the malaria MMG for onboarding, beginning with the pilot states. When the demands of the COVID-19 response decrease, more information about the guide will be presented on an eSHARE call.
  • CDC expects to open 10 additional guides for onboarding in 2020:
    • mumps
    • pertussis
    • varicella
    • TB and LTBI
    • babesiosis
    • trichinellosis
    • Lyme and tickborne rickettsial diseases (Lyme/TBRD)
    • healthcare-associated infections multi-drug resistant organisms (HAI MDRO)
    • foodborne and diarrheal diseases (FDD)
    • respiratory invasive bacterial diseases (RIBD).
  • Several NNDSS HL7 message mapping guides—generic v2, arboviral, hepatitis, and malaria—are currently open for general onboarding. Access them at the NNDSS HL7 Case Notification Resource Center.

 NMI eSHARE Updates

  • The next NMI eSHARE session is scheduled for Tuesday, 5/19/20, from 3:00 to 3:30 PM ET. Please note that CDC is changing the duration of the session to 30 minutes to be mindful of everyone’s time during the response. The May topic will be announced at a later time.
  • Access past eSHARE presentations and details about future events at the NMI eSHARE website.

 Join a Cohort to Jumpstart Your MMG Implementations!

  • The NMI APHL Technical Assistance team provides technical assistance to help groups, or cohorts, of public health agencies build and implement NNDSS HL7 case notification messages.
  • Cohorts of 4–6 public health agencies focus on specific message mapping guides.
  • APHL subject matter experts guide participants through planning, gap analysis, data extraction, HL7 message creation, and validation. At completion, public health agencies will be ready to begin onboarding.
  • For those interested in joining a cohort, please email the CDC Electronic Data Exchange mailbox at edx@cdc.gov.

Production HL7 Case Notification Messages

Production HL7 Case Notification Messages

Arboviral v1.3


Congenital Syphilis and STD

  • MMGs and artifacts are available on the NNDSS HL7 Case Notification Resource Center.
    • Please note that new versions of the STD and CS guides will be available soon.
    • Jurisdictions implementing current versions of the guides will be allowed to onboard with them.
    • Jurisdiction users who have not yet implemented the current versions of the guides should wait until the new versions are released.  
  • CDC opened the current versions of the guides for onboarding in January and is working with a set of states that have completed pre-onboarding work.
    • There are 4 pilot jurisdictions in production for STD and CS. North Carolina is the latest jurisdiction in production for CS. Congratulations, North Carolina!
    • Alabama, Michigan, South Carolina, and Wisconsin are engaged in onboarding.

Foodborne and Diarrheal Diseases  

 Generic v2

Healthcare-Associated Infections, Multi-Drug Resistant Organisms


Lyme and Tickborne Rickettsial Diseases


Mumps and Pertussis


Tuberculosis and Latent Tuberculosis Infection


Developing HL7 Case Notification Messages

Developing HL7 Case Notification Messages

Bacterial Special Pathogens (Requirements Analysis)

  • CDC will be submitting an Office of Management and Budget (OMB) non-substantive change request for new data elements for brucellosis, anthrax, leptospirosis, and Hansen’s disease once approval has been received for the current 2019 revision package.
  • COVID-19 support issues have delayed the external review comment period to gather jurisdiction feedback. CDC will provide more details as soon as they are available.

Carbon Monoxide Poisoning (CO) (Stage II—Pilot Test-ready)

  • CDC is verifying the test case scenario worksheet and the MMG data element priority list before distributing the pilot test-ready version of the MMG.
  • An additional data element has been identified by the CDC program for inclusion in an OMB non-substantive change request.

Lead Poisoning (Requirements Analysis)

  • No new updates at this time.

Listeriosis (Stage I—Draft)

  • No new updates at this time.

Measles (Stage III—Final MMG)

Respiratory Invasive Bacterial Disease (Stage III—Final MMG)

Rubella and Congenital Rubella Syndrome (Stage III—Final MMG)



Jurisdiction Implementation of NNDSS HL7 Case Notification Messages

This chart shows the status of state public health departments who are piloting, receiving technical assistance, onboarding, or in production for HL7 case notification messages developed as part of the NNDSS Modernization Initiative.

Upcoming Events


NMI Notes provides monthly news updates about the National Notifiable Diseases Surveillance System (NNDSS) Modernization Initiative (NMI). It is a collaboration by the Centers for Disease Control and Prevention (CDC), Council of State and Territorial Epidemiologists (CSTE), and Association of Public Health Laboratories (APHL).

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Page last reviewed: May 6, 2020