NIOSH Skin Notation Profiles

NIOSH Scientific Information Quality – Peer Review Agenda

Document

NIOSH Skin Notation Profiles

NIOSH Docket 153-C

Required Elements for Initial Public Posting

Subject: NIOSH Skin Notation Profiles

Purpose: Provide information about the health risks associated with dermal contact and uptake of specific high priority workplace chemicals.

Timing of Review: Public comment period for 14 profiles: May 2015 – June 2015. Public comment period for 10 profiles: November 2013 – January 2014, Peer review during public comment period.

Primary Disciplines or Expertise Needed for Review: Toxicology, risk assessment, industrial hygiene, occupational medicine

Type of Review: Individual

Number of Reviewers: 2-3 reviewers per Skin Notation Profile

Reviewers Selected by: NIOSH

Public Nominations Requested for Reviewers: No

Opportunities for the Public to Comment: Yes

Peer Reviewers Provided with Public Comments Before Their Review: No

 

Peer Reviewers

Acrylic Acid:

William E. Luttrell, Ph.D.
Associate Professor and
Chair, Department of Chemistry and Physics,
Oklahoma Christian University
Expertise: toxicology, chemistry

Gloria Post, Ph.D.
Research Scientist
New Jersey Department of Environmental Protection
Expertise: toxicology, human health risk assessment

Glenn Sipes, Ph.D.
Professor Emeritus, Department of Pharmacology
University of Arizona, Tucson, AZ
Expertise: pharmacology, toxicology

Atrazine:

Larry K. Lowry, Ph.D.
Professor, Department of Occupational and Environmental Medicine
The University of Texas Health Science Center at Tyler
Expertise: chemistry, toxicology

Sean Semple, Ph.D.
Senior Lecturer, Scottish Centre for Indoor Air
Division of Applied Health Sciences
University of Aberdeen, Scotland
Expertise: respiratory health

Glenn Sipes, Ph.D.
Professor Emeritus, Department of Pharmacology
University of Arizona at Tucson
Expertise: pharmacology, toxicology

Catechol:

William E. Luttrell, Ph.D.
Associate Professor of Chemistry
Chair, Department of Chemistry and Physics
Oklahoma Christian University
Expertise: toxicology, chemistry

Carrie Redlich, MD, MPH
Professor of Medicine
Director, Occupational and Environmental Medicine Program
Yale School of Medicine
Expertise: occupational medicine

Sean Semple, Ph.D.
Senior Lecturer, Scottish Centre for Indoor Air
Division of Applied Health Sciences
University of Aberdeen, Scotland
Expertise: respiratory health

Chlorinated camphene:

Frank A. Barile, Ph.D., R.Ph.
Professor, Dept. Pharmaceutical Sciences
St. John’s University College of Pharmacy and Health Sciences
Expertise: applied and clinical toxicology

Larry K. Lowry, Ph.D.
Professor, Department of Occupational and Environmental Medicine
The University of Texas Health Science Center at Tyler
Expertise: chemistry, toxicology

Gloria Post, Ph.D.
Research Scientist
New Jersey Department of Environmental Protection
Expertise: toxicology, human health risk assessment

Dichlorvos: 

Frank A. Barile, Ph.D., R.Ph.
Professor, Dept. Pharmaceutical Sciences
St. John’s University College of Pharmacy and Health Sciences
Expertise: applied and clinical toxicology

Larry Kenneth Lowry, Ph.D.
Professor, Department of Occupational and Environmental Medicine
The University of Texas Health Science Center at Tyler
Expertise: chemistry, toxicology

Karin Pacheco, MD, MSPH
Associate Professor, Division of Environmental and Occupational Health Sciences,
National Jewish Medical and Research Center, Denver, CO.

Dioxathion:

William E. Luttrell, Ph.D.
Associate Professor of Chemistry
Chair, Department of Chemistry and Physics
Oklahoma Christian University
Expertise: toxicology, chemistry

Carrie Redlich, MD, MPH
Professor of Medicine
Director, Occupational and Environmental Medicine Program
Yale School of Medicine
Expertise: occupational medicine

Glenn Sipes, Ph.D.
Professor Emeritus, Department of Pharmacology
University of Arizona at Tucson
Expertise: pharmacology, toxicology

Ethyl p-nitrophenyl phenylphosphorothioate: 

Larry Kenneth Lowry, Ph.D.
Professor, Department of Occupational and Environmental Medicine
The University of Texas Health Science Center at Tyler
Expertise: chemistry, toxicology
William E. Luttrell, Ph.D.
Associate Professor of Chemistry
Chair, Department of Chemistry and Physics
Oklahoma Christian University
Expertise: toxicology, chemistry

Gloria Post, Ph.D.
Research Scientist
New Jersey Department of Environmental Protection
Expertise: toxicology, human health risk assessment

Morpholine: 

William E. Luttrell, Ph.D.
Associate Professor of Chemistry
Chair, Department of Chemistry and Physics
Oklahoma Christian University
Expertise: toxicology, chemistry

Karin Pacheco, MD, MSPH
Associate Professor, Division of Environmental and Occupational Health Sciences,
National Jewish Medical and Research Center, Denver, CO.

Carrie Redlich, MD, MPH
Professor of Medicine
Director, Occupational and Environmental Medicine Program
Yale School of Medicine
Expertise: occupational medicine

Pentachlorophenol:

William E. Luttrell, Ph.D.
Associate Professor of Chemistry
Chair, Department of Chemistry and Physics
Oklahoma Christian University
Expertise: toxicology, chemistry

Gloria Post, Ph.D.
Research Scientist
New Jersey Department of Environmental Protection, NJ
Expertise: toxicology, human health risk assessment

Carrie Redlich, MD, MPH
Professor of Medicine
Director, Occupational and Environmental Medicine Program
Yale School of Medicine
Expertise: occupational medicine

Sodium fluoroacetate:

Frank A. Barile, Ph.D., R.Ph.
Professor, Dept. Pharmaceutical Sciences
St. John’s University College of Pharmacy and Health Sciences
Expertise: applied and clinical toxicology

William E. Luttrell, Ph.D.
Associate Professor of Chemistry
Chair, Department of Chemistry and Physics
Oklahoma Christian University
Expertise: toxicology, chemistry

Sean Semple, Ph.D.
Senior Lecturer, Scottish Centre for Indoor Air
Division of Applied Health Sciences
University of Aberdeen, Scotland
Expertise: respiratory health

Charge to Peer Reviewers

The purpose of the technical review is to review the technical validity of the scientific information in these documents. If there are errors of fact, unsubstantiated claims, evidence of careless experimental work, inclusion of too much information already in the literature, or statements that are inaccurate, please note such in your review comments.

  1. Does this document clearly outline the systemic health hazards associated with exposures of the skin to the chemical? If not, what specific information is missing from the document?
  2. If the SYS or SYS (FATAL) notations are assigned, is the rationale and logic behind the assignment clear? If not assigned, is the logic clear why it was not (e.g., insufficient data, no identified health hazard)?
  3. Does this document clearly outline the direct (localized) health hazards associated with exposures of the skin to the chemical? If not, what specific information is missing from the document?
  4. If the DIR, DIR (IRR), or DIR (COR) notations are assigned, is the rationale and logic behind the assignment clear? If not assigned, is the logic clear why it was not (e.g., insufficient data, no identified health hazard)?
  5. Does this document clearly outline the immune-mediated responses (allergic response) health hazards associated with exposures of the skin to the chemical? If not, what specific information is missing from the document?
  6. If the SEN notation is assigned, is the rationale and logic behind the assignment clear? If not assigned, is the logic clear why it was not (e.g., insufficient data, no identified health hazard)?
  7. If the ID(SK) or SK were assigned, is the rationale and logic outlined within the document?
  8. Are the conclusions supported by the data?
  9. Are the tables clear and appropriate?
  10. Is the document organized appropriately? If not, what improvements are needed?
  11. Are you aware of any scientific data reported in governmental publications, databases, peer reviewed journals, or other sources that should be included within this document?
Page last reviewed: October 29, 2013