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Face mask use and persistence of livestock-associated Staphylococcus aureus nasal carriage among industrial hog operation workers and household contacts, USA.

Nadimpalli ML; Stewart JR; Pierce E; Pisanic N; Love DC; Hall D; Larsen J; Carroll KC; Tekle T; Perl TM; Heaney CD

Environ Health Perspect 2018 Dec; 126(12):127005

https://doi.org/10.1289/EHP3453

20054187

BACKGROUND: Industrial hog operation (IHO) workers may persistently carry antibiotic-resistant, livestock-associated Staphylococcus aureus in their nasal cavities. It is unclear whether IHO work activities can alter IHO workers' and their household members' exposure to these bacteria. OBJECTIVE: Our objective was to investigate the relationship of IHO work activities with persistence of antibiotic-resistant, livestock-associated S. aureus nasal carriage among IHO workers and their household members. METHODS: At biweekly intervals over 4 months, IHO workers and their household members completed questionnaires and provided nasal swabs that were assessed for S. aureus, multidrug-resistant S. aureus (MDRSA), and livestock-associated markers (tetracycline resistance, scn absence, spa type). We examined the association between transient and habitual IHO work activities and S. aureus nasal carriage outcomes. RESULTS: One hundred one IHO workers and 79 household members completed 1,456 study visits. Face mask use (each 25% increase) was associated with reduced odds of nasal carriage of MDRSA (odds ratio [OR]: 0.65 [95% confidence interval (CI): 0.46, 0.92], tetracycline-resistant S. aureus [OR = 0.74 (95% CI: 0.56, 0.97)], and S. aureus clonal complex (CC) 398/CC9 [OR = 0.77 (95% CI: 0.60, 0.99)]. IHO workers who ever (vs. never) gave pigs injections had higher odds of these outcomes. Among household members, living with an IHO worker who consistently (>/= 80% of the time) versus sometimes or never used a face mask was associated with reduced odds of carrying scn-negative S. aureus, tetracycline-resistant S. aureus, and S. aureus CC398/CC9 (OR range: 0.12. 0.20, all <0:05), and consistent IHO worker coveralls use was associated with reduced odds of household member MDRSA carriage only. Living with an IHO worker who habitually had contact with >/= 4,000 hogs (vs. < 4000) was associated with higher odds of household member livestock-associated S. aureus carriage. CONCLUSIONS: Consistent face mask use was associated with reduced exposure to antibiotic-resistant, livestock-associated S. aureus among IHO workers and their household members.

Staphylococcus aureus; Agriculture; Livestock; Animals; Humans; Men; Women; Children; Families; Questionnaires; Methicillin Resistant Staphylococcus aureus; MRSA; Statistical analysis; Animal handlers; Animal husbandry workers; Livestock industry; Agricultural workers; Take-home toxins; Face masks; Personal protective equipment; PPE; Antimicrobial resistance; Bacteria; Bacterial infections; Nasal cavity; Staphylococcus aureus infection

C. D. Heaney, Department of Environmental Health and Engineering, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA

EVHPAZ

20181201

Journal Article

cheaney1@jhu.edu

Grant

2019

Grant-Number-K01-OH-010193; Grant-Number-T42-OH-008428

12

0091-6765

Environmental Health Perspectives

NC; MD; TX

Johns Hopkins University, Baltimore, Maryland