NIOSHTIC-2 Publications Search

Response to Goodman et al.

Pinkerton LE; Yiin JH; Daniels RD; Fent KW

Am J Ind Med 2017 Feb; 60(2):223-225

https://doi.org/10.1002/ajim.22681

20049112

We thank the Journal for providing us the opportunity to respond to the letter from <a href="http://dx.doi.org/10.1002/ajim.22677"target="_blank">Goodman et al. [2017 Feb; 60(2):221-222]</a> regarding the conclusions of our mortality study among toluene diisocyanate (TDI)-exposed workers [Pinkerton et al., 2016 Aug; 59(8):630-643]. Goodman et al. conclude that <a href="http://dx.doi.org/10.1002/ajim.22622"target="_blank">our study</a> does not provide support for the carcinogenicity of TDI. We acknowledge that proof of a causal association between occupational exposure and cancer cannot be achieved by our study. Nonetheless, we contend that our findings add to a growing body of evidence of a causal association between TDI exposure and cancer and that dermal exposures could play an important role.

Toluene; Diisocyanates; Mortality studies; Mortality data; Mortality rates; Cancer; Skin exposure; Dermal exposures; Lung cancer

Lynne E. Pinkerton, MD, MPH, Industrywide Studies Branch, Division of Surveillance, Hazard Evaluations, and Field Studies, National Institute for Occupational Safety and Health, 1090 Tusculum Ave, R-15, Cincinnati, OH 45226

AJIMD8

26471-62-5

20170201

Other

lep5@cdc.gov

2017

2

0271-3586

DSHEFS; EID

American Journal of Industrial Medicine

OH