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Particulate matter, endotoxin, and worker respiratory health on large Californian dairies.
Mitchell-DC; Armitage-TL; Schenker-MB; Bennett-DH; Tancredi-DJ; Langer-CE; Reynolds-SJ; Dooley-G; Mehaffy-J; Mitloehner-FM
J Occup Environ Med 2015 Jan; 57(1):79-87
OBJECTIVE: To assess respiratory exposures and lung function in a cross-sectional study of California dairy workers. METHODS: Exposure of 205 dairy and 45 control (vegetable processing) workers to particulate matter and endotoxin was monitored. Pre- and postshift spirometry and interviews were conducted. RESULTS: Geometric mean inhalable and PM2.5 concentrations were 812 and 35.3 µg/m versus 481.9 and 19.6 µg/m, respectively, for dairy and control workers. Endotoxin concentrations were 329 EU/m or 1122 pmol/m and 13.5 EU/m or 110 pmol/m, respectively, for dairy and control workers. In a mixed-effects model, forced vital capacity decreased across a work shift by 24.5 mL (95% confidence interval, -44.7 to -4.3; P = 0.018) with log10 (total endotoxin) and by 22.0 mL (95% confidence interval, -43.2 to -0.08; P = 0.042) per hour worked. CONCLUSIONS: Modern California dairy endotoxin exposures and shift length were associated with a mild acute decrease in forced vital capacity.
Respiration; Respiratory-system-disorders; Pulmonary-system; Pulmonary-function; Pulmonary-system-disorders; Exposure-levels; Risk-factors; Lung; Lung-function; Agriculture; Agricultural-industry; Workers; Particulates; Endotoxins; Monitors; Spirometry; Statistical-analysis
Diane C. Mitchell, PhD, Department of Public Health Sciences, University of California, Davis, CA 95616
Cooperative Agreement; Agriculture
Issue of Publication
Agriculture, Forestry and Fishing
Journal of Occupational and Environmental Medicine
Colorado State University - Ft. Collins
Page last reviewed: April 12, 2019
Content source: National Institute for Occupational Safety and Health Education and Information Division