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Acute myeloid leukemia risk by industry and occupation.
Tsai-RJ; Luckhaupt-SE; Schumacher-P; Cress-RD; Deapen-DM; Calvert-GM
Leuk Lymphoma 2014 Nov; 55(11):2584-2591
Acute myeloid leukemia (AML) is the most common type of leukemia found in adults. Identifying jobs that pose a risk for AML may be useful for identifying new risk factors. A matched case-control analysis was conducted using California Cancer Registry data from 1988 to 2007. This study included 8999 cases of AML and 24 822 controls. Industries with a statistically significant increased AML risk were construction (matched odds ratio [mOR] = 1.13); crop production (mOR = 1.41); support activities for agriculture and forestry (mOR = 2.05); and animal slaughtering and processing (mOR = 2.09). Among occupations with a statistically significant increased AML risk were miscellaneous agricultural workers (mOR = 1.76); fishers and related fishing workers (mOR = 2.02); nursing, psychiatric and home health aides (mOR = 1.65); and janitors and building cleaners (mOR = 1.54). Further investigation is needed to confirm study findings and to identify specific exposures responsible for the increased risks.
Surveillance-programs; Cancer; Cancer-rates; Leukemogenesis; Men; Employee-exposure; Employee-health; Risk-factors; Lymphatic-cancer; Myeloid-tissue; Morbidity-rates; Epidemiology; Statistical-analysis; Construction; Construction-industry; Crop-spraying; Pesticides; Pesticides-and-agricultural-chemicals; Agricultural-industry; Agriculture; Forestry; Animals; Slaughterhouses; Agricultural-workers; Fishing-industry; Nursing; Health-care-personnel; Psychiatrists; Maintenance-workers; Author Keywords: Acute myeloid leukemia; industry; occupation; risk factors
Rebecca J.Tsai, National Institute for Occupational Safety and Health, 4676 Columbia Parkway, R-17, Cincinnati, OH 45226, USA
Issue of Publication
Agriculture, Forestry and Fishing
Leukemia & Lymphoma