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Acute myeloid leukemia risk by industry and occupation.

Authors
Tsai RJ; Luckhaupt SE; Schumacher P; Cress RD; Deapen DM; Calvert GM
Source
Leuk Lymphoma 2014 Nov; 55(11):2584-2591
Link
https://doi.org/10.3109/10428194.2014.894189
NIOSHTIC No.
20045434
Abstract
Acute myeloid leukemia (AML) is the most common type of leukemia found in adults. Identifying jobs that pose a risk for AML may be useful for identifying new risk factors. A matched case-control analysis was conducted using California Cancer Registry data from 1988 to 2007. This study included 8999 cases of AML and 24 822 controls. Industries with a statistically significant increased AML risk were construction (matched odds ratio [mOR] = 1.13); crop production (mOR = 1.41); support activities for agriculture and forestry (mOR = 2.05); and animal slaughtering and processing (mOR = 2.09). Among occupations with a statistically significant increased AML risk were miscellaneous agricultural workers (mOR = 1.76); fishers and related fishing workers (mOR = 2.02); nursing, psychiatric and home health aides (mOR = 1.65); and janitors and building cleaners (mOR = 1.54). Further investigation is needed to confirm study findings and to identify specific exposures responsible for the increased risks.
Keywords
Surveillance-programs; Cancer; Cancer-rates; Leukemogenesis; Men; Employee-exposure; Employee-health; Risk-factors; Lymphatic-cancer; Myeloid-tissue; Morbidity-rates; Epidemiology; Statistical-analysis; Construction; Construction-industry; Crop-spraying; Pesticides; Pesticides-and-agricultural-chemicals; Agricultural-industry; Agriculture; Forestry; Animals; Slaughterhouses; Agricultural-workers; Fishing-industry; Nursing; Health-care-personnel; Psychiatrists; Maintenance-workers; Author Keywords: Acute myeloid leukemia; industry; occupation; risk factors
Contact
Rebecca J.Tsai, National Institute for Occupational Safety and Health, 4676 Columbia Parkway, R-17, Cincinnati, OH 45226, USA
CODEN
LELYEA
Publication Date
20141101
Document Type
Journal Article
Email Address
rtsai@cdc.gov
Fiscal Year
2015
Identifying No.
M122014
Issue of Publication
11
ISSN
1042-8194
NIOSH Division
DSHEFS
Priority Area
Agriculture, Forestry and Fishing
Source Name
Leukemia & Lymphoma
State
OH; CA
Page last reviewed: May 11, 2023
Content source: National Institute for Occupational Safety and Health Education and Information Division