Work schedules and 11-year progression of carotid atherosclerosis in middle-aged Finnish men.
Wang-A; Arah-OA; Kauhanen-J; Krause-N
Am J Ind Med 2015 Jan; 58(1):1-13
OBJECTIVES: This study investigated the relationship between different work schedules and progression of carotid atherosclerosis, an early indicator of cardiovascular disease (CVD). METHODS: We studied 621 men, aged 42-60 years, in the prospective Kuopio Ischemic Heart Disease Risk Factor Study cohort. Using multivariable regressions adjusting for 22 covariates including total time worked during follow-up, we evaluated the associations of baseline work schedules with 11-year progression of ultrasonographically assessed carotid intima-media thickness (IMT), and their variation by preexisting CVD. RESULTS: Standard daytime work, weekend shifts, and evening/night/rotating shifts were associated with 31%, 37%, and 33% increases in IMT, respectively. Compared to daytime workers, weekend workers experienced a faster progression of carotid atherosclerosis [relative change ratio (RCR)=1.05, 95% CI: 1.00-1.09)]. This ratio was higher among men who had preexisting CVD. CONCLUSIONS: Weekend shifts, more than standard daytime work, appear to accelerate carotid atherosclerosis progression among middle-aged Finnish men, especially those with pre-existing CVD.
Humans; Men; Workers; Work-environment; Age-groups; Cardiovascular-system; Cardiovascular-system-disease; Cardiovascular-system-disorders; Cardiovascular-disease; Diseases; Shift-work; Shift-workers; Statistical-analysis; Demographic-characteristics; Sociological-factors;
Author Keywords: occupational health; overtime work; prospective study; weekend shift; work-life balance
Niklas Krause, MD, PhD, Department of Environmental Health Sciences and Department of Epidemiology, The Fielding School of Public Health, UCLA, Box 95-1772; 56-071CHS, 650 Charles E.Young Drive South,Los Angeles,CA 90095-1772
American Journal of Industrial Medicine
University of California Los Angeles