Prevalence of airflow obstruction in U.S. adults aged 40-79 years: NHANES data 1988-1994 and 2007-2010
Doney-B; Hnizdo-E; Dillon-CF; Paulose-Ram-R; Tilert-T; Wolz-M; Beeckman-Wagner-L-A
COPD 2015 Aug; 12(4):355-365
BACKGROUND: The study evaluated the change in the prevalence of airflow obstruction in the U.S. population 40-79 years of age from years 1988-1994 to 2007-2010. METHODS: Spirometry data from two representative samples of the U.S. population, the National Health and Nutrition Examination Surveys (NHANES) conducted in 1988-1994 and 2007-2010, were used. The American Thoracic Society/European Respiratory Society (ATS/ERS) criteria were used to define airflow obstruction. RESULTS: Based on ATS/ERS criteria, the overall age-adjusted prevalence of airflow obstruction among adults aged 40-79 years decreased from 16.6% to 14.5% (p < 0.05). Significant decreases were observed for the older age category 60-69 years (20.2% vs. 15.4%; p < 0.01), for males (19.0% vs. 15.4%; p < 0.01), and for Mexican American adults (12.7% vs. 8.4%; p < 0.001). The prevalence of moderate and more severe airflow obstruction decreased also (6.4% vs. 4.4%; p < 0.01). Based on ATS/ERS criteria, during 2007-2010, an estimated 18.3 million U.S. adults 40-79 years had airflow obstruction, 5.6 million had moderate or severe airflow obstruction and 1.4 million had severe airflow obstruction. CONCLUSIONS: The overall age-adjusted prevalence of airflow obstruction among U.S. adults aged 40-79 years decreased from 1988-1994 to 2007-2010, especially among older adults, Mexican Americans, and males.
Respiratory-system-disorders; Pulmonary-system-disorders; Lung-disorders; Lung-disease; Lung-function; Airway-obstruction; Airway-resistance; Health-surveys; Information-retrieval-systems; Spirometry; Statistical-analysis; Age-factors; Age-groups; Men; Racial-factors; Chronic-inflammation; Pulmonary-function-tests; Pulmonary-function; Demographic-characteristics; Surveillance;
Author Keywords: airflow obstruction; chronic obstructive pulmonary disease; NHANES; spirometry
Brent Doney, Division of Repiratory Disease Studies, National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention (NIOSH), 1095 Willowdale Road, Morgantown, West Virginia 26505, USA
COPD: Journal of Chronic Obstructive Pulmonary Disease