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Exposure to volatile organic compounds in healthcare settings.

LeBouf-RF; Virji-MA; Saito-R; Henneberger-PK; Simcox-N; Stefaniak-AB

Occup Environ Med 2014 Sep; 71(9):642-650

http://dx.doi.org/10.1136/oemed-2014-102080

20044652

OBJECTIVES: To identify and summarise volatile organic compound (VOC) exposure profiles of healthcare occupations. METHODS: Personal (n=143) and mobile area (n=207) evacuated canisters were collected and analysed by a gas chromatograph/mass spectrometer to assess exposures to 14 VOCs among 14 healthcare occupations in five hospitals. Participants were volunteers identified by their supervisors. Summary statistics were calculated by occupation. Principal component analysis (PCA) was used to reduce the 14 analyte inputs to five orthogonal factors and identify occupations that were associated with these factors. Linear regressions were used to assess the association between personal and mobile area samples. RESULTS: Exposure profiles differed among occupations; ethanol had the highest geometric mean (GM) among nursing assistants (approximately 4900 and approximately 1900 µg/m3, personal and area), and 2-propanol had the highest GM among medical equipment preparers (approximately 4600 and approximately 2000 µg/m3, personal and area). The highest total personal VOC exposures were among nursing assistants (approximately 9200 µg/m3), licensed practical nurses (approximately 8700 µg/m3) and medical equipment preparers (approximately 7900 µg/m3). The influence of the PCA factors developed from personal exposure estimates varied by occupation, which enabled a comparative assessment of occupations. For example, factor 1, indicative of solvent use, was positively correlated with clinical laboratory and floor stripping/waxing occupations and tasks. Overall, a significant correlation was observed (r=0.88) between matched personal and mobile area samples, but varied considerably by analyte (r=0.23-0.64). CONCLUSIONS: Healthcare workers are exposed to a variety of chemicals that vary with the activities and products used during activities. These VOC profiles are useful for estimating exposures for occupational hazard ranking for industrial hygienists as well as epidemiological studies.

Volatiles; Organic-compounds; Health-care; Exposure-levels; Health-care-personnel; Medical-personnel; Chromatographic-analysis; Mass-spectrometry; Medical-facilities; Statistical-analysis; Sampling; Chemical-properties; Solvents; Epidemiology; Industrial-hygienists

Dr Ryan F LeBouf, National Institute for Occupational Safety and Health, 1095 Willowdale Road, Morgantown, WV 26505

OEMEEM

64-17-5; 107-02-8

20140901

Journal Article

rlebouf@cdc.gov

2014

M072014

9

1351-0711

DRDS

Occupational and Environmental Medicine

WV; CT