Population-based study of asthma in immigrant farm worker families: the role of home environment and social context (MICASA Study).
Muni-S; Tancredi-DJ; Stoecklin-Marois-M; Hennessy-Burt-T; Schenker-M; MICASA
Am J Respir Crit Care Med 2013 May; 187(Meeting Abstracts):A2078
RATIONALE: Asthma prevalence increases within a generation after immigration to the US in Mexican Americans, supporting a prominent role for environment or other non-genetic causes. Studies to date have not evaluated home environment and social context in Latino rural adult asthma. OBJECTIVE: To assess the relationship between asthma prevalence and environmental, psychosocial, and migration factors. METHODS: We conducted a population-based prospective cohort investigation of individual, occupational and environmental risks and other factors associated with respiratory health in 843 adult Latino farm workers and spouses. Data collected from 2006-2007 at the baseline assessment is presented here. RESULTS: We found 10.1% asthma prevalence in our population that differed based on nativity; US-born 35.1%, Mexico 7.9% and other Central America 11.2%. In a multiple regression model the odds ratio for asthma was 0.16 (95% CI, 0.08-0.32) for birth in Mexico and 0.25 (95% CI, 0.14-0.45) for birth in Central American as compared to birth in US. Asthma was associated with home environmental exposures with an odds ratio of 3.27 (95% CI 1.47-7.28) for cat; and 1.73 (95% CI, 1.03-2.90) for cockroaches. Asthma was associated with social factors with an odds ratio of 2.05 (95% CI, 1.07-3.95) for high perceived stress; and 3.65 (95% CI, 2.37-5.63) for depressive symptoms. CONCLUSIONS: Asthma prevalence increases 3-fold after one generation with immigration to the US, and our study showed that home environment and social context are important risk factors for asthma in this population. Future research to ameliorate asthma in rural or Latino populations should address psychosocial and environmental factors in concert.
Agriculture; Agricultural-workers; Agricultural-processes; Agricultural-chemicals; Agricultural-industry; Farmers; Bronchial-asthma; Racial-factors; Respiratory-system-disorders; Pulmonary-system-disorders; Lung-disorders; Environmental-exposure; Environmental-factors; Environmental-contamination; Sociological-factors; Psychological-factors; Families; Risk-factors; Exposure-assessment; Mental-health; Job-stress
S. Muni, UCSF, San Francisco, CA
Grant; Cooperative Agreement; Agriculture
American Journal of Respiratory and Critical Care Medicine
University of California - Davis