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Evaluation of a single-channel nasal pressure device to assess obstructive sleep apnea risk in laboratory and home environments.

Crowley KE; Rajaratnam SM; Shea SA; Epstein LJ; Czeisler CA; Lockley SW; Harvard Work Hours, Health and Safety Group
J Clin Sleep Med. 2013 Feb; 9(2):109-116
STUDY OBJECTIVES: To evaluate the sensitivity and specificity of a portable single-channel (intra-nasal pressure) sleep apnea device (ApneaLink) in both the laboratory and at home for assessment of sleep apnea risk in comparison with standard polysomnography (PSG). METHODS: Fifty-five participants underwent simultaneous recordings of standard PSG and ApneaLink in the laboratory. Of these, 38 participants also used the ApneaLink device in their own homes for one night. PSG respiratory events were scored using standard criteria. Intra-nasal pressure signals were analyzed using the ApneaLink automated computerized algorithm provided to yield estimates of airflow for detection of apneas and hypopneas. Apnea-hypopnea indices (AHI) were compared. RESULTS: There was high sensitivity and specificity for the ApneaLink AHI when compared to simultaneous PSG at comparable AHI levels (AHI = 15 events/h; sensitivity 100%, specificity 92%; positive and negative predictive values 70% and 100%, respectively). Home-measured ApneaLink AHI sensitivity and specificity were also reliable when compared with PSG (AHI = 5, 81% and 77%, respectively; AHI = 15, 67% and 91%), and improved slightly when two nights' data were used (AHI = 5, 88% and 85%; AHI = 15, 67% and 93%). CONCLUSIONS: The ApneaLink demonstrated good sensitivity and specificity in quantifying AHI when compared to PSG in a population with and without confirmed OSA. This simple, easy-to-use device may be useful in de novo large-scale occupational or underserved community OSA diagnostic programs to identify those with unambiguous disease who need immediate treatment or indicate those who may be at increased risk of OSA.
Sleep-disorders; Nasal-cavity; Breathing; Monitoring-systems; Medical-monitoring; Medical-equipment; Laboratory-testing; Signal-devices; Air-flow; Humans; Airway-obstruction; Equipment-reliability; Analytical-instruments; Author Keywords: Home monitoring; obstructive sleep apnea; ApneaLink; AHI
Steven W. Lockley, Ph.D., Division of Sleep Medicine, 221 Longwood Avenue, BLI438, Boston, MA 02115-5817
Publication Date
Document Type
Journal Article
Email Address
Funding Type
Fiscal Year
Identifying No.
Grant-Number-R01-OH-008496; M082013
Issue of Publication
Source Name
Journal of Clinical Sleep Medicine
Performing Organization
Brigham and Women's Hospital - Boston, Massachusetts
Page last reviewed: April 1, 2022
Content source: National Institute for Occupational Safety and Health Education and Information Division