NIOSHTIC-2 Publications Search

Evaluation of silicosis in response to highest task silica exposure with imputed values where no measurements were made.

Authors
Grimsley-F; Rice-C; Ayer-H; Clark-S; Succop-P; Rinsky-R
Source
American Industrial Hygiene Conference and Exposition, May 20-25, 2000, Orlando, Florida. Fairfax, VA: American Industrial Hygiene Association, 2000 May; :80
NIOSHTIC No.
20041649
Abstract
More than one million workers are exposed annually to silica in the workplace. The purpose and specific aims of this study were to investigate ways to estimate silica exposure in unsampled tasks and to evaluate the relationship between highest task silica exposure imputed and the development of silicosis. Data from the North Carolina Dusty Trades, a unique resource for exposure-response studies of the effects of silica exposure, is the basis for the study. Three methods of imputation were used. The methods were estimating exposures based on the mean exposure at sampled commodity-specific tasks, the lower bound of the 95% confidence interval of the median of commodity-specific tasks, and maximum likelihood estimate. The three imputation methods are described and presented. The results of this study indicate that the highest task-related silica exposure is related to the development of silicosis with an odds ratio of 2.22 and is statistically significant (p=0.001). These results can serve as a guide to changes in sampling methods and targeted control techniques that should be implemented to decrease disease in the workplace.
Keywords
Exposure-assessment; Epidemiology; Silica-dusts; Silicon-compounds; Silicosis; Respiratory-system-disorders; Pulmonary-system-disorders; Lung-disorders; Analytical-processes; Employee-exposure; Industrial-exposures; Occupational-exposure; Task-performance; Information-retrieval-systems; Dose-response; Dust-exposure; Dust-sampling; Analytical-methods; Sampling-methods; Dust-control
CAS No.
7631-86-9; 14808-60-7
Publication Date
20000520
Document Type
Abstract
Funding Type
Grant
Fiscal Year
2000
Identifying No.
Grant-Number-R03-OH-003775
NIOSH Division
DSHEFS
Source Name
American Industrial Hygiene Conference and Exposition, May 20-25, 2000, Orlando, Florida
State
OH; FL; VA
Performing Organization
University of Cincinnati
Page last reviewed: May 5, 2020
Content source: National Institute for Occupational Safety and Health Education and Information Division