NIOSHTIC-2 Publications Search
Detection of polycyclic aromatic hydrocarbons (PAHS) in skin wipe samples of automotive mechanic. trainees.
Booth-Jones-A; Neumeister-C; Talaska-G
American Industrial Hygiene Conference and Exposition, May 20-25, 2000, Orlando, Florida. Fairfax, VA: American Industrial Hygiene Association, 2000 May; :47
Epidemiologic evidence suggests that automobile and truck mechanics are at increased risk of bladder cancer. For mechanics, used gasoline engine oil (UGEO) is a major occupational exposure. UGEOs contain polycyclic aromatic hydrocarbons (PAHs) formed during combustion in engine operation. Because these PAHs have low volatility, mechanics have potential dermal exposure. Many PAHs found in UGEO are known or probable carcinogens. The purpose of this study was to determine whether PAHs were detected in skin wipe samples of automotive mechanic trainees. Sixty-nine participants were enrolled from vocational schools in Ohio and Kentucky. Participants completed an informed consent; 36 were included in the intervention group and were provided with training and special cleansers; and 33 were placed in the nonintervention group. Skin wipe samples were collected by filter paper after participants massaged com oil into their hands. Successive skin wipe samples were taken from those in the intervention group after the intervention was in place. Samples were extracted by ultrasonification in acetonitrile, filtered, and stored until analysis. Sixteen model PAHs measured by fluorescence and UV detectors were naphthalene, acenaphthylene, acenaphthene, fluorene, phenanthrene, anthracene, fluoranthene (FLUOR), pyrene, benz[a] anthracene (BAA), chrysene, benzo[b]fluoranthene, benzo[k]fluoranthene, benzo[a] pyrene (BAP), dibenz[a.,h] anthracene (DAHA), benzo[ghi]perylene, and indeno[1,2,3-cd]pyrene (lNDENO). Eighty-one percent of those in the intervention group provided at least two skin-wipe samples. Measurable amounts of PAHs were detected in 90% of the samples. The concentrations of PAHs ranged from 54.51 microg/microL to 0.18 microg/microL for FLUOR, BAA, BAP, DAHA, and INDENO, which are carcinogens. Mean levels of BAP and DAHA were 4.63 microg/microL and 1.88 microg/microL, respectively; more than 13 participants had levels above these mean values. This study shows that PAHs from UGEO are present in hand-wipe samples of automotive trainees. Excess PAH exposure is hazardous, and interventions should be designed to reduce contact.
Automotive-industry; Automobile-repair-shops; Mechanics; Polycyclic-aromatic-hydrocarbons; Skin-absorption; Skin-exposure; Employee-exposure; Epidemiology; Bladder-cancer; Cancer; Motor-vehicles; Petroleum-oils; Sampling; Humans; Training; Oils; Combustion-engines; Combustion-products; Carcinogens; Health-hazards; Hazardous-materials; Exposure-levels; Fluorenes; Fluoroanthrenes; Phenanthrenes; Naphthalenes; Anthracenes; Chrysenes; Benzopyrenes; Benzanthracenes
75-05-8; 85-01-8; 120-12-7; 129-00-0; 56-55-3; 205-99-2; 207-08-9; 50-32-8; 53-70-3; 191-24-2; 193-39-5; 83-32-9; 86-73-7; 206-44-0; 218-01-9; 91-20-3; 208-96-8
American Industrial Hygiene Conference and Exposition, May 20-25, 2000, Orlando, Florida
OH; FL; VA