A sampling and analytical method for the simultaneous determination of multiple organonitrogen pesticides in air.
Kennedy-ER; Lin-JJ; Reynolds-JM; Perkins-JB
American Industrial Hygiene Conference and Exposition, May 19-23, 1997, Dallas, Texas. Fairfax, VA: American Industrial Hygiene Association, 1997 May; :52
Lack of accurate exposure estimates has been a weak link in associations of pesticide exposures with occupational illnesses. To provide more accurate airborne exposure information, an air sampling and analytical method was developed for organonitrogen pesticides using a combined filter and XAD-2 sorbent sampler and high performance liquid chromatography (HPLC)-ultraviolet detection (UV). The method was evaluated for 14 organonitrogen pesticides by NIOSH evaluation guidelines and procedures. Evaluation experiments addressed limits of detection and quantitation, analytical recovery, sampler capacity, sample stability and precision and bias over a range of 12 to 240 g per sample. Samples were stable when stored for up to 30 days under either ambient or refrigerated conditions. Based on the finding of this work, 10 (aldicarb, captan, carbaryl, carbofuran, chlorpropham, diuron, formetanate, methiocarb, oxamyl, propham) of the 14 compounds studied can be successfully determined simultaneously using one method with an accuracy of better than +25% of the true value with 95% confidence. Two other compounds (carbendazim/benomyl, methomyl) can be measured with the same accuracy over a more limited concentration range. The remaining two compounds (propoxur, thiobencarb) may meet this criterion, but additional samples would need to be included in the data analysis. With the current data, these two compounds can be determined with an accuracy of better than + 27% of the true value with 95% confidence, This method will be included in the next edition of the NIOSH Manual of Analytical Methods as Method 5601.
Exposure-levels; Exposure-limits; Pesticides; Airborne-dusts; Air-contamination; Air-sampling; Air-samples; Analytical-methods; Organo-nitrogen-compounds; Filters; Liquid-chromatography
116-06-3; 133-06-2; 63-25-2; 1563-66-2; 10605-21-7; 17804-35-2; 16752-77-5; 114-26-1
American Industrial Hygiene Conference and Exposition, May 19-23, 1997, Dallas, Texas