An evaluation of a dose rate parameter in occupational radiation epidemiologic studies.
Taulbee-TD; Spitz-HB; Neton-JW; Chen-PH
Arbete och Halsa 2001 Jun; 2001(10):453-456
Introduction: Risk estimates for occupational radiation exposure are primarily based upon studies of atomic bomb survivors and other persons who received instantaneous or acute radiation exposure. In contrast, occupational radiation exposure tends to be received at a low intensity and in a fractionated or protracted manner. Multiple studies of animals have clearly demonstrated that fractionated and low intensity exposure to gamma radiation results in a reduced rate of cancer incidence compared to acute exposures (8,5,7,2). The International Commission on Radiological Protection (ICRP) has developed the Dose and Dose Rate Effectiveness Factor (DDREF) to accommodate the observed decrease in cancer incidence associated with fractionated gamma exposures. Although the ICRP (3) recommends a value of 2 for the DDREF, they also recognize that this value is somewhat arbitrary and in need of additional validation. The United States National Institute for Occupational Safety and Health (NIOSH) is conducting an Occupational Energy Research Program to investigate health effects in workers who are exposed to radiation. In this analysis, we compare the conventional dose rate calculation to a new method, which is shown to be a better description of the intensity (dose rate) of the cumulative dose for epidemiological studies.
Epidemiology; Exposure-assessment; Employee-exposure; Risk-analysis; Radiation; Nuclear-radiation; Acute-exposure; Gamma-radiation; Exposure-methods; Cancer-rates; Dose-response; Occupational-exposure; Radiation-exposure; Worker-health; Biological-effects; Health-programs
T. D. Taulbee, Health-Related Energy Research Branch, National Institute for Occupational Safety and Health, Cincinnati, OH USA
Hagsberg-M; Knave-B; Lillienberg-L; Westberg-H
Arbete och Halsa (X2001 - exposure assessment in epidemiology and practice, June 10-13, 2001, Göteborg, Sweden)