Ethical issues in molecular epidemiologic research.
Molecular epidemiology: principles and practices. Rothman N, Hainaut P, Schulte P, Smith M, Boffetta P, Perera F, eds. Lyon, France: International Agency for Research on Cancer, IARC Scientific Publication, No 163, 2012 Jul; :9-22
Contemporary and future molecular epidemiologic research will be conducted against a backdrop of massive biological databases, comprehensive and longitudinal electronic medical records, large medical care expenditures, aging populations, emerging infectious diseases in some countries, and global climate change. These conditions will influence the ethical issues that arise in molecular epidemiologic research. Will these issues differ from epidemiologic or scientific research in general? Some of the issues will be unique to molecular epidemiology, and others will be relevant to all research. If the conduct of molecular epidemiology is to contribute to medical and publ ic health research and have a positive impact, there is a need for investigators to be aware of and adhere to the generally accepted ethical principles discussed in this chapter. Further, it is important to realize that data that will be made available in the future from new genomic technology will continue to pose challenges to the ethical conduct of molecular epidemiologic research. Therefore, researchers will need to be aware of the dynamic nature of guidelines and regulations.
Epidemiology; Molecular-biology; Molecular-structure; Diseases; Biomarkers; Exposure-levels; Public-health; Biological-factors; Biological-systems; Medical-research
Rothman-N; Hainaut-P; Schulte-P; Smith-M; Boffetta-P; Perera-F
Molecular epidemiology: principles and practices