The results from these analyses clearly demonstrate a strong exposure-response relationship between chrysotile exposure and mortality from asbestosis and lung cancer, which is not surprising given the results from previous studies. The exposure-response relationship for lung cancer appeared to be linear on a multiplicative scale, whereas the exposure-response relationship for asbestosis appeared to be sub-linear. There was no statistical evidence for a threshold in either the lung cancer or asbestosis model. Thus the results from this analysis fail to provide any support for arguments that have been made for a threshold for the effects of chrysotile asbestos on lung cancer and asbestosis risks (Browne, 1986). Based on this analysis, the predictions of excess lifetime risk for white males exposed for 45 years at the recently revised OSHA standard of 0.1 fibers cc--1 was predicted to be approximately 5 per 1000 for lung cancer and 2 per 1000 for asbestosis. The lung cancer risks estimated in this analysis were substantially higher than what was observed in previous analyses of Quebec chrysotile miners and millers (McDonald et al., 1980, 1994). The reasons for these widely varying results are not known.
We take your privacy seriously. You can review and change the way we collect information below.
These cookies allow us to count visits and traffic sources so we can measure and improve the performance of our site. They help us to know which pages are the most and least popular and see how visitors move around the site. All information these cookies collect is aggregated and therefore anonymous. If you do not allow these cookies we will not know when you have visited our site, and will not be able to monitor its performance.
Cookies used to make website functionality more relevant to you. These cookies perform functions like remembering presentation options or choices and, in some cases, delivery of web content that based on self-identified area of interests.
Cookies used to track the effectiveness of CDC public health campaigns through clickthrough data.
Cookies used to enable you to share pages and content that you find interesting on CDC.gov through third party social networking and other websites. These cookies may also be used for advertising purposes by these third parties.