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Peripheral nerve function and lower extremity muscle power in older men.

Authors
Ward-RE; Caserotti-P; Faulkner-K; Boudreau-R; Cawthon-PM; Newman-AB; Cauley-JA; Strotmeyer-ES
Source
Gerontologist 2011 Nov; 51(Suppl 2):112
NIOSHTIC No.
20040832
Abstract
Decline in muscle power with age may be partly due to lower peripheral nerve (PN) function, particularly number and firing rate of motor units. We assessed cross-sectional relationships between maximal power/kg body weight (Nottingham power rig) and sensorimotor nerve function (peroneal/sural nerve conduction, monofilament testing, symptoms) in 568 men (mean age=77.2+/-5.1, BMI=28.2+/-4.0, power=1.87+/-0.6watts/kg) from the Osteoporotic Fractures in Men (MrOS) Study in Pittsburgh, PA. Covariates included age, body composition, comorbidities (e.g. diabetes, ankle arm index), lifestyle factors (e.g. physical activity), and grip strength. Higher compound muscle action potential (CMAP) and detection of 1.4g monofilament were associated with greater power/kg (both p<0.05). Having >2 PN symptoms (numbness/tingling, stabbing/burning/pain, open/persistent sores/gangrene) was associated with lower power/kg (p<0.01). Sural nerve conduction and motor latency were not associated with power/kg after adjustment. In these older men, CMAP, monofilament detection and PN symptoms were related to power/kg and may identify muscle function problems.
Keywords
Nerve-function; Peripheral-nervous-system; Men; Age-factors; Age-groups; Extremities; Muscle-function; Physical-capacity; Sensory-motor-system; Peripheral-motor-system; Body-weight; Neuromotor-function; Neuromuscular-function
Publication Date
20111102
Document Type
Abstract
Fiscal Year
2012
ISSN
0016-9013
NIOSH Division
NPPTL
Source Name
Gerontologist
State
PA; MD; CA
Page last reviewed: April 12, 2019
Content source: National Institute for Occupational Safety and Health Education and Information Division