Physicochemical and toxicological properties of commercial carbon blacks modified by reaction with ozone.
Peebles-BC; Dutta-PK; Waldman-WJ; Villamena-FA; Nash-K; Severance-M; Nagy-A
Environ Sci Technol 2011 Dec; 45(24):10668-10675
Ozonation of two commercial carbon blacks (CBs), Printex 90 (P90) and Flammruss 101 (F101), was carried out and changes in their morphology, physical properties, and cytotoxicity were examined. The hypothesis examined was that different methods of manufacture of CBs influence their chemical reactivity and toxicological properties. Structural changes were examined by X-ray photoelectron spectroscopy, infrared spectroscopy, Raman spectroscopy, and electron paramagnetic resonance spectroscopy (EPR). Introduction of surface oxygen functionality upon ozonation led to changes in surface charge, aggregation characteristics, and free radical content of the CBs. However, these changes in surface functionality did not alter the cytotoxicity and release of inflammation markers upon exposure of the CBs to murine macrophages. Interaction of macrophages with F101 resulted in higher levels of inflammatory markers than P90, and the only structural correlation was with the higher persistent radical concentration on the F101.
Airborne-dusts; Airborne-particles; Air-contamination; Pollutants; Toxins; Models; Chemical-composition; Cytotoxic-effects; Cytotoxicity
Prabir K. Dutta, Department of Chemistry, The Ohio State University, 100 West 18th Avenue, Columbus, OH 43210
Environmental Science and Technology
The Ohio State University