Approaches for calculating power for case-cohort studies.
Kim-MY; Xue-X; Du-Y
Biometrics 2006 Sep; 62(3):929-933
An approach for determining the power of a case-cohort study for a single binary exposure variable and a low failure rate was recently proposed by Cai and Zeng (2004, Biometrics 60, 1015-1024). In this article, we show that computing power for a case-cohort study using a standard case-control method yields nearly identical levels of power. An advantage of the case-control approach is that existing sample size software can be used for the calculations. We also propose an additional formula for computing the power of a case-cohort study for the situation when the event is not rare.
Epidemiology; Group-dynamics; Exposure-levels; Exposure-limits; Carcinogens; Statistical-analysis; Risk-factors; Environmental-exposure; Models; Mathematical-models; Analytical-models; Molecular-biology; Humans; Men; Women; Radiation-exposure; Radiation;
Author Keywords: Case-cohort design; Power; Sample size
Mimi Y. Kim, Division of Biostatistics, Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, New York 10461
Albert Einstein College of Medicine