Risk and significance of chest radiograph and pulmonary function abnormalities in an elderly cohort of former nuclear weapons workers.
Mikulski MA; Hartley PG; Sprince NL; Sanderson WT; Lourens S; Worden NE; Wang K; Fuortes LJ
J Occup Environ Med 2011 Sep; 53(9):1046-1053
OBJECTIVE: To estimate prevalence and risk factors for International Labour Organization radiographic abnormalities, and assess relationship of these abnormalities with spirometry results in former Department of Energy nuclear weapons workers. METHODS: Participants were offered chest x-ray (CXR) and lung function testing. Three occupational medicine physicians read CXRs. RESULTS: Forty-five (5.9%) of 757 screened workers were found to have isolated parenchymal abnormalities on CXR and this rate is higher than that in many Department of Energy studies. Parenchymal and pleural and isolated pleural abnormalities were found in 19 (2.5%) and 37 (4.9%) workers, respectively, and these rates are lower than those in other Department of Energy studies to date. Lung function impairment was associated with radiographic abnormalities. CONCLUSIONS: This study found an elevated rate of parenchymal abnormalities compared to other DoE populations but the effect of age or other causes could not be ruled out.
Radiographic-analysis; Nuclear-radiation; Nuclear-hazards; Workers; Work-environment; Risk-factors; Exposure-limits; Exposure-levels; Epidemiology; Pulmonary-function; Pulmonary-system; Pulmonary-system-disorders; X-ray-diagnosis; Lung-function; Lung; Pneumoconiosis; Radionuclides; Ionizing-radiation; Barium-compounds; Beryllium-compounds; Nitrates; Asbestos-fibers
Marek Mikulski, MD, MPH, PhD, The University of Iowa, 2213 Westlawn, Iowa City, IA 52242
7440-39-3; 7440-41-7; 1332-21-4; 10022-31-8
Journal of Occupational and Environmental Medicine
University of Iowa