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Effort-reward imbalance, overcommitment, and cellular immune measures among white-collar employees.
Nakata-A; Takahashi-M; Irie-M
Biol Psychol 2011 Dec; 88(2-3):270-279
We investigated whether chronic job stress, i.e., effort-reward imbalance (ERI) and overcommitment is associated with cellular immunity among 190 male and 157 female white-collar daytime employees (mean age 38; range 22-69 years). Participants provided a blood sample for the measurement of circulating immune (natural killer (NK), B, and T) cell counts and NK cell cytotoxicity (NKCC) and completed a questionnaire survey during April to June 2002. Stepwise multiple linear regression analyses revealed that NK cells were inversely associated with effort (Beta = -.230; p = .013), reward (Beta = .169; p = .047), and ERI (Beta = -.182; p = .047) scores but not with overcommitment in men; reward score was positively associated with NKCC (Beta = .167; p = .049) and inversely associated with B cells (Beta = -.181; p = .030). No significant associations were found in women. Although the picture remains less clear in women, our findings suggest a potential immunological pathway linking adverse working conditions and stress-related disorders in men.
Back-injuries; Ergonomics; Injury-prevention; Medical-equipment; Medical-facilities; Medical-personnel; Medical-services; Muscular-disorders; Musculoskeletal-system; Musculoskeletal-system-disorders; Physiological-effects; Physiological-factors; Physiological-function; Posture; Training; Author Keywords: musculoskeletal disorders; back injuries; ergonomic interventions; moving equipment
Akinori Nakata, Division of Applied Research and Technology, National Institute for Occupational Safety and Health, 4676 Columbia Parkway, MS-C24, Cincinnati, OH 45226
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