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First periodic review of scientific and medical evidence related to cancer for the World Trade Center Health Program.

Connick KD; Enright P; Middendorf PJ; Piacentino J; Reissman DB; Sawyer T; Souza K
Cincinnati, OH: U.S. Department of Health and Human Services, Public Health Service, Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, DHHS (NIOSH) Publication No. 2011-197, 2011 Jul; :1-93
This review is based on three information sources. First, a systematic search was conducted for peer-reviewed findings on exposure and cancer resulting from the September 11, 2001, terrorist attacks that have been published in the scientific and medical literature between September 11, 2001, and July 1, 2011. Second, findings and recommendations related to cancer were solicited from the WTC Clinical Centers of Excellence and Data Centers, the WTC Health Registry at the New York City Department of Health and Mental Hygiene, and the New York State Department of Health. Third, information from the public about cancer was solicited through a Request for Information published in the Federal Register on March 8, 2011, and March 29, 2011. Overall, this inaugural review of cancer presents findings from the peer-reviewed scientific and medical literature about exposures and cancer resulting from the September 11, 2001, terrorist attacks. In addition, the review provides the status of planned and ongoing research efforts to address questions about cancer related to the exposures resulting from the terrorist attacks. Specifically, Chapter I describes how the bibliographic search of scientific and medical findings was conducted. Chapter II summarizes the information contained in scientific and medical publications about September 11, 2001, exposures. Chapter III cites the very few peer-reviewed study reports that contain any quantitative data about cancer as a health outcome resulting from September 11, 2001, exposures. In Chapter IV, a primer on cancer epidemiology is presented. In Chapter V, input from the public and from the WTC Clinical Centers of Excellence, the WTC Health Registry, and the New York State Department of Health about cancer is presented. Chapter VI discusses the challenge of determining whether an observed association between one or more of the September 11, 2001, exposure variables and the health outcome of cancer is causal. Finally, the review includes updates from researchers about current studies of cancer. It is expected that the second periodic review of cancer will be conducted in early to mid-2012 to capture any emerging findings about exposures and cancer in responders and survivors affected by the September 11, 2001, terrorist attacks.
Cancer; Carcinogens; Emergency-responders; Fire-fighters; Paramedical-services; Police-officers; Asbestos-dust; Nanotechnology; Metals; Metallic-dusts; Metal-dusts; Particulate-dust; Particulates; Organic-compounds; Organic-dusts; Volatiles; Polycyclic-aromatic-hydrocarbons; Silica-dusts; Risk-analysis; Fibrous-dusts; Fibrous-glass
1332-21-4; 14808-60-7; 67-64-1; 71-43-2; 106-99-0; 74-87-3; 100-42-5; 12001-29-5
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DHHS (NIOSH) Publication No. 2011-197
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National Institute for Occupational Safety and Health
Page last reviewed: March 18, 2022
Content source: National Institute for Occupational Safety and Health Education and Information Division