A new passive sampler for regulated workplace ketones.
Tsai-S-W; Que Hee-SS
Am Ind Hyg Assoc J 2000 Nov/Dec; 61(6):808-814
A new solid sorbent passive air sampler for ketones has a silicone membrane atop a diffusion cylindrical path length of 1.1 cm and diameter 1.3 cm above a pellet of Tenax TA coated with 10% (w/w) O-(2,3,4,5,6-pentafluorobenzyl)hydroxylamine hydrochloride. Vapors of known concentrations approximating their workplace permissible exposure limits of Occupational Safety and Health Administration-regulated ketones at a relative humidity (RH) of 3 +/- 1% were generated by a syringe pump connected to a dynamic air dilution system connected to an exposure chamber that allowed measurement of face velocities, temperatures, exposing vapor concentrations, and RHs. The O-oxime derivative was desorbed with hexane, and an aliquot injected for gas chromatographic analysis on a nonpolar capillary column by mass spectrometric or electron capture detection. The experimental passive sampler sampling rates in milliliters per minute at 25 degrees C were 4.07 +/- 0.49, cyclohexanone; 6.30 +/- 0.59, diethyl ketone; 6.31 +/- 0.31, ethyl n-butyl ketone; 3.78 +/- 0.25, methyl n-amyl ketone; 3.43 +/- 0.19, methyl n-butyl ketone; 6.48 +/- 0.64, methyl ethyl ketone; 4.37 +/- 0.43, methyl isopropyl ketone; and 4.57 +/- 0.17, methyl n-propyl ketone. These preliminary data show that sterically unhindered ketones can be sampled by the passive sampler as well as aldehydes.
Air-flow; Air-samplers; Air-sampling; Air-sampling-equipment; Air-sampling-techniques; Air-temperature; Aldehydes; Chromatographic-analysis; Exposure-assessment; Exposure-levels; Exposure-limits; Gas-chromatography; Hexanes; Mass-spectrometry; Quantitative-analysis; Sampling-methods; Spectroscopes; Statistical-analysis; Vapor-detectors; Vapors; Workplace-monitoring; Workplace-studies;
Author Keywords: adsorption; gas chromatography; ketone; oxime; passive sampler; personal sampling
Shane S. Que Hee, Department of Environmental Health Sciences and UCLA Center for Occupational and Environmental Health, UCLA School of Public Health, 10833 Le Conte Avenue, Los Angeles, CA 90095-1772
Research Tools and Approaches: Exposure Assessment Methods
American Industrial Hygiene Association Journal
University of California Los Angeles, Los Angeles, CA