NIOSHTIC-2 Publications Search
The 2010 update to the NIOSH list of hazardous drugs.
Pharm Purch Prod 2010 Nov; 7(11):28-30
Side Effects of Hazardous Drugs: We are all aware that there are possible side effects of antineoplastic drugs found in patients treated with high doses, but there are published reports that associate a number of acute effects from exposure to hazardous drugs at any number of levels. These effects include skin rash, headache, hair loss, mucous membrane irritation, and others. Adverse reproductive effects also have been demonstrated in health care workers exposed to these drugs. A number of studies have reported significant increases in markers of genetic damage such as chromosomal damage and other types of DNA damage. Although many antineoplastic drugs are known or suspected carcinogens, cancer has not been studied in any systematic way in health care workers.
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