During the past decade, the characteristics and number of adolescent workers has changed little. Several studies were conducted during this time documenting the patterns, scope, and effect of work among young individuals in the United States. Part-time employment may benefit youth by imparting positive work values, reinforcing the importance of academic skills for future career success, providing a better understanding of the workplace, increasing contact with adults, and building character. Negative aspects of youth employment include threats to completion of developmental tasks and education, injury, toxic exposure, and illness. The enactment of regulations and resulting change in the nature of youth employment has contributed to a substantial decrease in youth-related occupational fatality and injury. However, youth workers continue to suffer fatal and nonfatal occupational injuries with most injuries occurring in the retail industry. Efforts should be made to develop innovative interventions tailored to young workers that focus on surveillance, advocacy, education, and research to decrease workplace injury and illness.