A conceptual and historical framework for molecular epidemiology.
Molecular epidemiology: principles and practices. Schulte PA, Perera FP, eds. San Diego, CA: Academic Press, 1993 Apr; :3-44
We are in the era of molecular research. Between 1970 and 1990, the number of medical journals with the word "molecular" in the title grew from 31 to 90, signaling that the understanding of biologic phenomena has proceeded to the molecular level. This evolution resulted from advances in molecular biology, genetics, analytical chemistry, and other basic sciences. It is now possible to detect smaller amounts of analytes and contaminants and smaller biological changes, as well as to identify mechanisms at the cellular and molecular levels. Progress in the molecular approach to biology and medicine has stimulated and excited both the public and researchers, who now believe these advances can be applied to the study, prevention, and control of health risks faced by human populations. The term "molecular epidemiology" may be used to describe such an approach: the incorporation of molecular, cellular, and other biologic measurements into epidemiologic research.
Epidemiology; Molecular-biology; Molecular-epidemiology; Cellular-function; Biological-function; Subcellular-structure; Preventive-medicine; Disease-prevention; Disease-control
Molecular epidemiology: principles and practices