Urinary 1-hydroxypyrene levels in offshore workers.
Hopf-NB; Kirkeleit-J; Kramer-SL; Moen-B; Succop-P; Genter-MB; Carreón-T; Mack-J; Talaska-G
Int Arch Occup Environ Health 2010 Jan; 83(1):55-59
Objectives: To compare differences in pre- and post-shift urinary 1-hydroxypyrene (1OHP) levels as a measure of internal dose of polycyclic aromatic hydrocarbons (PAHs) between two groups of oil production workers offshore assumed to be exposed to PAH, and to compare the exposed group to an unexposed control group. Methods: Participants' (n = 42) urine samples, collected over a study period of three consecutive 12-h work days (pre-shift on the first day and post-shift on the third day), were analyzed using high performance liquid chromatography (HPLC) with fluorescence detection. Analysis of covariance was used in the statistical models. Results: (1) Post-shift 1OHP levels were significantly higher in the exposed workers compared to the controls. (2) Tank workers and process operators did not show statistically significant different post-shift 1OHP levels. Conclusion: Altogether, this study indicates the presence of a low level PAH exposure among offshore oil production workers.
Biological-monitoring; Polychlorinated-aromatic-hydrocarbons; Oil-industry; Humans; Urinalysis;
Author Keywords: Polycyclic aromatic hydrocarbons; PAH; 1-Hydroxypyrene; Offshore; Biological monitoring; Crude oil exposure
International Archives of Occupational and Environmental Health
University of Cincinnati