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Skeletal muscle injury versus adaptation with aging: novel insights on perplexing paradigms.
Baker BA; Cutlip RG
Exerc Sport Sci Rev 2010 Jan; 38(1):10-16
A growing body of data supports a view that skeletal muscle's response after mechanical loading does not always result in the classically reported "injury response." Furthermore, current evidence supports a model of muscle adaptation and/or maladaptation, distinct from overt injury, in which myofiber degeneration and inflammation do not contribute as significantly as once reported even in aged populations.
Age-factors; Biological-factors; Injuries; Muscle-function; Muscle-physiology; Muscle-stress; Muscular-disorders; Musculoskeletal-system; Musculoskeletal-system-disorders; Skeletal-movement; Skeletal-stress; Skeletal-system; Author Keywords: mechanical loading; stretch shortening contractions; high-intensity resistance training; muscle adaptation; myofiber degeneration; myofiber regeneration; inflammation
Robert G. Cutlip, CDC, National Institute for Occupational Safety and Health, Health Effects Laboratory Division, 1095 Willowdale Rd., Morgantown, WV 26505
Issue of Publication
Exercise and Sport Sciences Reviews
Page last reviewed: May 8, 2020Content source: National Institute for Occupational Safety and Health Education and Information Division