Skeletal muscle injury versus adaptation with aging: novel insights on perplexing paradigms.
Baker BA; Cutlip RG
Exerc Sport Sci Rev 2010 Jan; 38(1):10-16
A growing body of data supports a view that skeletal muscle's response after mechanical loading does not always result in the classically reported "injury response." Furthermore, current evidence supports a model of muscle adaptation and/or maladaptation, distinct from overt injury, in which myofiber degeneration and inflammation do not contribute as significantly as once reported even in aged populations.
Age-factors; Biological-factors; Injuries; Muscle-function; Muscle-physiology; Muscle-stress; Muscular-disorders; Musculoskeletal-system; Musculoskeletal-system-disorders; Skeletal-movement; Skeletal-stress; Skeletal-system;
Author Keywords: mechanical loading; stretch shortening contractions; high-intensity resistance training; muscle adaptation; myofiber degeneration; myofiber regeneration; inflammation
Robert G. Cutlip, CDC, National Institute for Occupational Safety and Health, Health Effects Laboratory Division, 1095 Willowdale Rd., Morgantown, WV 26505
Exercise and Sport Sciences Reviews