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Atopy and upper and lower airway disease among former World Trade Center workers and volunteers.
de la Hoz-RE; Shohet-MR; Wisnivesky-JP; Bienenfeld-LA; Afilaka-AA; Herbert-R
J Occup Environ Med 2009 Sep; 51(9):992-995
OBJECTIVE: A large number of workers seemed to have developed upper and lower airway disease (UAD and LAD, respectively) in relation to their occupational exposures at the World Trade Center (WTC) disaster site. This study examined atopy as a risk factor for presumably WTC-related UAD and LAD. METHODS: Atopy was examined in 136 former WTC workers and volunteers by radioallergosorbent test, skin prick testing, or both. Overall prevalence of atopy was estimated, and bivariate and multivariate logistic regression analyses were conducted to examine associations of atopy with WTC-related UAD and LAD. RESULTS: Atopy was prevalent in 54.4% of these WTC workers. Atopy was associated with higher symptom severity scores for both WTC-related UAD and LAD. Atopy was a predictor of WTC-related UAD but not LAD. Early arrival at the WTC site, and pre-2001 asthma diagnosis were predictors of LAD. CONCLUSION: The prevalence of atopy in this population is similar to what has been described for the general U.S. population. Atopy seemed to be a risk factor for presumably WTC-related UAD but not for LAD.
Allergens; Exposure-assessment; Exposure-methods; Inhalation-studies; Lung; Lung-disorders; Occupational-exposure; Occupational-health; Occupational-respiratory-disease; Pulmonary-system-disorders; Respiratory-hypersensitivity; Respiratory-irritants; Respiratory-system-disorders; Statistical-analysis; Worker-health; Work-operations
Rafael E. de la Hoz, MD, MPH, The Mount Sinai School of Medicine, WTC Monitoring and Treatment Program, One Gustave L. Levy Place, Box 1059, New York, NY 10029
Issue of Publication
Journal of Occupational and Environmental Medicine
Mount Sinai School of Medicine of New York University
Page last reviewed: March 11, 2019
Content source: National Institute for Occupational Safety and Health Education and Information Division