Prospective comparison of tuberculin skin test and QuantiFERON-TB Gold In-Tube assay for the detection of latent tuberculosis infection among healthcare workers in a low-incidence setting.
Cummings KJ; Smith TS; Shogren ES; Khakoo R; Nanda S; Bunner L; Smithmyer A; Soccorsi D; Kashon ML; Mazurek GH; Friedman LN; Weissman DN
Infect Control Hosp Epidemiol 2009 Nov; 30(11):1123-1126
We compared the results of the tuberculin skin test with the results of the QuantiFERON-TB Gold In-Tube (QFT-GIT) assay among 182 low-risk healthcare workers. Overall agreement and specificity were high, but the tests did not agree on positive results. Only 2 of 5 positive QFT-GIT assay results could be confirmed with repeat analyses. Indeterminate results were associated with potential immunosuppression.
Infectious-diseases; Health-care-personnel; Health-care; Respiratory-system-disorders; Diagnostic-tests; Bacterial-disease; Bacteria; Microorganisms; Skin-tests
Kristin J. Cummings, MD, MPH, National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, 1095 Willowdale Road, MS-2800, Morgantown, WV 26505
Infection Control and Hospital Epidemiology