Diagnostic and therapeutic applications of lytic phages.
Mandeville-R; Griffiths-M; Goodridge-L; McIntyre-L; Ilenchuk-TT
Anal Lett 2003 Oct; 36(15):3241-3259
The ability of lytic phages to rapidly kill and lyse infected bacteria, the specificity of phages for particular bacteria, and the ability of phages to increase in number during the infection process make phages excellent potential diagnostic and therapeutic agents for fighting bacterial disease. However, temperate phages are of little use in phage diagnostics and therapy
Bacteria; Bacterial-cultures; Bacterial-disease; Bacterial-dusts; Bacterial-infections; Bactericides; Bacteriology; Bacteriostasis; Diagnostic-tests; Infection-control; Infectious-diseases; Phagocytes; Phagocytic-activity; Genotoxic-effects; Genotoxicity; Food; Food-contaminants; Food-handlers; Food-processing; Food-processing-equipment; Food-processing-industry; Food-processing-workers; Food-services; Food-spoilage; Pathogenesis; Pathogenicity; Pathogens; Pathology; Diagnostic-tests; Viral-diseases; Viral-infections;
Author Keywords: Lytic phages; Phages; Diagnosis; Therapy; Bacteria; Reporter genes; Luciferase
R. Mandeville, Department of Animal Science, University of Wyoming, Laramie, Wyoming
Colorado State University - Fort Collins