Determination of the effective dermal penetration barrier pH of porcine skin.
J Vet Pharmacol Ther 2009 Jan; 32(4):407-410
The purpose of the present analysis was to determine the operational or effective pH of the skin relative to dermal penetration by using an existing QSPeR model and assessing its best model fit as a function of penetrant's log DpH.
Absorption-rates; Acid-mists; Acids; Chemical-hypersensitivity; Chemical-properties; Chemical-reactions; Dermatitis; Dermatology; Exposure-assessment; Exposure-levels; Exposure-methods; Skin; Skin-absorption; Skin-exposure; Skin-irritants; Skin-sensitivity
Dr Jim Riviere, Center for Chemical Toxicology Research and Pharmacokinetics, 4700 Hillsborough Street, North Carolina State University, Raleigh, NC 27606
Work Environment and Workforce: Mixed Exposures; Manufacturing
Journal of Veterinary Pharmacology and Therapeutics
North Carolina State University, Raleigh, North Carolina