NIOSHTIC-2 Publications Search
Genetics and workplace issues.
Genomics and Environmental Regulation: Science, Ethics, and Law. Sharp RR, Marchant GE, Grodsky JA, eds., Baltimore, MD: Johns Hopkins University Press, 2008 Oct; :141-168
In this chapter, genetics related to the workplace will be considered in three categories of use: research, practice, and regulation or litigation (Table 9.1). To further explore these categories, I will consider them with respect to inherited genetic factors and acquired genetic effects-a common classification scheme for genetic risks. Inherited genetic effects pertain to somatic and germ cell DNA transmitted through mitosis or meiosis, respectively. These are the processes of cell division that involve the formation of either new body cells (mitosis) or new reproductive cells in the gonads (meiosis). Acquired genetic effects involve modification of genetic material over time and can include genetic damage or genetic expression resulting from workplace or environmental exposures. When measured in a biological specimen, either type of information can be considered a genetic biomarker (Ashford et al., 1990).
Genetics; Gene-mutation; Genes; Genetic-factors; Biomarkers
Book or book chapter
Sharp-RR; Marchant-GE; Grodsky-JA
Genomics and Environmental Regulation: Science, Ethics, and Law